Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos

  1. Gil de Montes Rojas, Enrique
Dirigida por:
  1. Inmaculada Robina Ramirez Director/a
  2. Antonio José Moreno Vargas Director/a

Universidad de defensa: Universidad de Sevilla

Fecha de defensa: 24 de mayo de 2020

Tribunal:
  1. Fernando Hernández Mateo Presidente/a
  2. Elena Díez Martín Secretario/a
  3. José Luis de Paz Carrera Vocal
  4. Maris Turks Vocal
  5. Francisco Corzana López Vocal

Tipo: Tesis

Teseo: 618164 DIALNET lock_openIdus editor

Resumen

The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.