Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos

  1. Gil de Montes Rojas, Enrique
unter der Leitung von:
  1. Inmaculada Robina Ramirez Doktorvater/Doktormutter
  2. Antonio José Moreno Vargas Doktorvater/Doktormutter

Universität der Verteidigung: Universidad de Sevilla

Fecha de defensa: 24 von Mai von 2020

Gericht:
  1. Fernando Hernández Mateo Präsident/in
  2. Elena Díez Martín Sekretär/in
  3. José Luis de Paz Carrera Vocal
  4. Maris Turks Vocal
  5. Francisco Corzana López Vocal

Art: Dissertation

Teseo: 618164 DIALNET lock_openIdus editor

Zusammenfassung

The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.