Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos
- Gil de Montes Rojas, Enrique
- Inmaculada Robina Ramirez Director/a
- Antonio José Moreno Vargas Director/a
Universitat de defensa: Universidad de Sevilla
Fecha de defensa: 24 de de maig de 2020
- Fernando Hernández Mateo President/a
- Elena Díez Martín Secretari/ària
- José Luis de Paz Carrera Vocal
- Maris Turks Vocal
- Francisco Corzana López Vocal
Tipus: Tesi
Resum
The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.