Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos
- Gil de Montes Rojas, Enrique
- Inmaculada Robina Ramirez Director
- Antonio José Moreno Vargas Director
Defence university: Universidad de Sevilla
Fecha de defensa: 24 May 2020
- Fernando Hernández Mateo Chair
- Elena Díez Martín Secretary
- José Luis de Paz Carrera Committee member
- Maris Turks Committee member
- Francisco Corzana López Committee member
Type: Thesis
Abstract
The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.