Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos

  1. Gil de Montes Rojas, Enrique
Supervised by:
  1. Inmaculada Robina Ramirez Director
  2. Antonio José Moreno Vargas Director

Defence university: Universidad de Sevilla

Fecha de defensa: 24 May 2020

Committee:
  1. Fernando Hernández Mateo Chair
  2. Elena Díez Martín Secretary
  3. José Luis de Paz Carrera Committee member
  4. Maris Turks Committee member
  5. Francisco Corzana López Committee member

Type: Thesis

Teseo: 618164 DIALNET lock_openIdus editor

Abstract

The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.