Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos
- Gil de Montes Rojas, Enrique
- Inmaculada Robina Ramirez Directeur/trice
- Antonio José Moreno Vargas Directeur/trice
Université de défendre: Universidad de Sevilla
Fecha de defensa: 24 mai 2020
- Fernando Hernández Mateo President
- Elena Díez Martín Secrétaire
- José Luis de Paz Carrera Rapporteur
- Maris Turks Rapporteur
- Francisco Corzana López Rapporteur
Type: Thèses
Résumé
The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.