Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos

  1. Gil de Montes Rojas, Enrique
Zuzendaria:
  1. Inmaculada Robina Ramirez Zuzendaria
  2. Antonio José Moreno Vargas Zuzendaria

Defentsa unibertsitatea: Universidad de Sevilla

Fecha de defensa: 2020(e)ko maiatza-(a)k 24

Epaimahaia:
  1. Fernando Hernández Mateo Presidentea
  2. Elena Díez Martín Idazkaria
  3. José Luis de Paz Carrera Kidea
  4. Maris Turks Kidea
  5. Francisco Corzana López Kidea

Mota: Tesia

Teseo: 618164 DIALNET lock_openIdus editor

Laburpena

The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.