Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos
- Gil de Montes Rojas, Enrique
- Inmaculada Robina Ramirez Zuzendaria
- Antonio José Moreno Vargas Zuzendaria
Defentsa unibertsitatea: Universidad de Sevilla
Fecha de defensa: 2020(e)ko maiatza-(a)k 24
- Fernando Hernández Mateo Presidentea
- Elena Díez Martín Idazkaria
- José Luis de Paz Carrera Kidea
- Maris Turks Kidea
- Francisco Corzana López Kidea
Mota: Tesia
Laburpena
The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.