Síntesis y reactividad de sistemas [2.2.1]bicíclicos. Estudio de la bioconjugación de proteínas con azanorbornadienos
- Gil de Montes Rojas, Enrique
- Inmaculada Robina Ramirez Director
- Antonio José Moreno Vargas Director
Universidade de defensa: Universidad de Sevilla
Fecha de defensa: 24 de maio de 2020
- Fernando Hernández Mateo Presidente/a
- Elena Díez Martín Secretario/a
- José Luis de Paz Carrera Vogal
- Maris Turks Vogal
- Francisco Corzana López Vogal
Tipo: Tese
Resumo
The study of the reactivity of [2.2.1](hetero)bicyclic systems [(7-heteronorbornanes and 7- (hetero)norbornadienes)] and the use of this kind of molecules in the bioconjugation of proteins is presented in this Thesis. It should be pinted out that all studies with bicyclic systems have been carried out with racemic mixtures, although for simplicity in this thesis only one of the enantiomers is represented.