Síntesis y análisis conformacional de o-glicoaminoacidos y o-glicopeptidos modelo de interés biológico

Duration of the 01 of October of 2006 to 30 of September of 2009

Researchers

Foto de Alberto
Alberto
Avenoza Aznar
Responsable
Foto de Carlos
Carlos
Aydillo Miguel
Foto de Jesús Héctor
Jesús Héctor
Busto Sancirián
Foto de Javier
Javier
Carreras Pérez-Aradros
Foto de Francisco
Francisco
Corzana López
Foto de Alberto
Alberto
Fernández Tejada
Foto de María Luisa
María Luisa
García de Luis
Foto de Gonzalo
Gonzalo
Jiménez Osés
Foto de Gadea
Gadea
Mata Martínez
Foto de Jesús Manuel
Jesús Manuel
Peregrina García
Foto de María del Mar
María del Mar
Zurbano Asensio

Publications related to the project

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2010

  1. Síntesis y reactividad en procesos de metátesis de sistemas azabiciclo [2.2.n] sustituidos en posición cabeza de puente

    Javier Carreras Pérez-Aradros

  2. Cyclobutane serine amino acid derivatives as 5-hydroxyproline precursors

    ARKIVOC

2009

  1. Beta-o-glicosilación de péptidos que incorporan aminoácidos no naturales

    Alberto Fernández Tejada

  2. A Highly Regioselectivity Ring Opening Metathesis-Cross Metathesis Process Modulated by the Electronic Effects of the Cross Metathesis Partner: an Entry to Quaternary Prolines

    Journal of Organic Chemistry

  3. The Nature and Sequence of the Amino Acid Aglycone Strongly Modulates the Conformation and Dynamics Effects of Tn Antigen's Clusters

    Chemistry - A European Journal

  4. Stabilizing Unusual Conformations in Small Peptides and Glucopeptides using a Hydroxylated Cyclobutane Amino Acid

    Organic and Biomolecular Chemistry

  5. Insights into the geometrical features underlying beta-O-GIcNAc glycosylation: Water pockets drastically modulate the interactions between the carbohydrate and the peptide backbone

    Chemistry - A European Journal

  6. A novel multistep mechanism for the stereocontrolled ring opening of hindered sulfamidates: Mild, green, and efficient reactivity with alcohols

    Chemistry - A European Journal

  7. Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides

    Journal of Organic Chemistry

2008

  1. Glicopéptidos modelo que incorporan el antígeno Tn. Síntesis y análisis conformacional

    María Luisa García de Luis

  2. Formal [2+2] Cycloaddition of 2-Acylaminoacrylates with Vinyl Sulfides. An Approach to Cyclobutane-alfa-Amino Acids as S-Phenylcysteine Analogues

    Synthesis (Stuttgart)

  3. Highly chemoselective reactions on hindered sulfamidates with oxygenated nucleophiles

    Tetrahedron: Asymmetry

  4. Non-Natural Amino Acids as Modulating Agents of the Conformational Space of Model Glycopeptides

    Chemistry - A European Journal

  5. Synthesis of 2-amino-1,3-diols incorporating the cyclobutane ring

    Tetrahedron

  6. Nuevas aportaciones al estudio estructural de glicopéptidos

    Anales de la Real Sociedad Española de Química

2007

  1. Síntesis y reactividad de sulfatos y suldamidatos cíclicos

    Gonzalo Jiménez Oses

  2. Regioselective Ring-Opening Metathesis-Cross Metathesis of Bridgehead-Substituted 7-Azanorbornene

    Organic Letters

  3. Synthesis of Azabicyclo[2.2.n]alkane Systems as Analogues of 3-[1-Methyl-2-(S)-pyrrolidinylmethoxy]pyridine (A-84543)

    Journal of Organic Chemistry

  4. Theoretical Evidence of Pyramidalized Bicyclic Serine Enolates in Highly Diastereoselective Alkylations

    Chemistry - A European Journal

  5. Role of the Countercation in Diastereoselective Alkylations of Pyramidalized Bicyclic Serine Enolates. An Easy Approach to alfa-Benzylserine

    Journal of Organic Chemistry

  6. Serine versus Threonine Glycosylation: The Methyl Group Causes a Drastic Alteration on the Carbohydrate Orientation and on the Surrounding Water Shell

    Journal of the American Chemical Society