date_range Duración del 01 de enero de 2016 al 31 de diciembre de 2018 (36 meses)
euro 77.440,00 EUR

De ámbito Nacional.

Investigadores/as

Foto de Gonzalo
Gonzalo
Jiménez Osés
Responsable

Publicaciones relacionadas con el proyecto (19)

Mostrar por tipología

2019

  1. Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents

    Nature Protocols

  2. Elusive Dehydroalanine Derivatives with Enhanced Reactivity

    ChemBioChem

2018

  1. Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1- S- and C1- O-Nucleophiles

    Journal of Organic Chemistry

  2. Oxygen by Carbon Replacement at the Glycosidic Linkage Modulates the Sugar Conformation in Tn Antigen Mimics

    ACS Omega

  3. Cell-Penetrating Peptides Containing Fluorescent d-Cysteines

    Chemistry - A European Journal

  4. Chemo- and Regioselective Lysine Modification on Native Proteins

    Journal of the American Chemical Society

2017

  1. Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

    Angewandte Chemie International

  2. A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst

    Journal of the American Chemical Society

  3. Metal-Free [2 + 2]-Photocycloaddition of (Z)-4-Aryliden-5(4H)-Oxazolones as Straightforward Synthesis of 1,3-Diaminotruxillic Acid Precursors: Synthetic Scope and Mechanistic Studies

    ACS Sustainable Chemistry and Engineering

  4. Multiple Mechanisms for the Thermal Decomposition of Metallaisoxazolin-5-ones from Computational Investigations

    Journal of Organic Chemistry

  5. 1,3-Dipolar Cycloaddition Reactions of Low-Valent Rhodium and Iridium Complexes with Arylnitrile N-Oxides

    Journal of Organic Chemistry

  6. Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation

    Journal of the American Chemical Society

2016

  1. A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels–Alder Bioorthogonal Labeling in Live Cells

    Angewandte Chemie International

  2. Tn Antigen Mimics Based on sp2-Iminosugars with Affinity for an anti-MUC1 Antibody

    Organic Letters

  3. Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition

    Organic Letters

  4. Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders

    Journal of the American Chemical Society

  5. A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2

    Nature Chemical Biology

  6. Computations Reveal That Electron-Withdrawing Leaving Groups Facilitate Intramolecular Conjugate Displacement Reactions by Negative Hyperconjugation

    Journal of Organic Chemistry

  7. Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents

    Nature Communications