Alberto
Avenoza Aznar
CATEDRÁTICO DE UNIVERSIDAD
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Instituto de Química Orgánica General
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Química Orgánica General (13)
2024
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Detection of Tumor-Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes
Angewandte Chemie - International Edition
2019
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
2018
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Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
Journal of the American Chemical Society, Vol. 140, Núm. 31, pp. 9952-9960
2017
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The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18255-18261
2016
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Mucin Architecture behind the Immune Response: Design and Evaluation of an Antitumor Vaccine Derived from an Unnatural MUC1 Fragment
Chemical Science, Vol. 7, Núm. 3, pp. 2294
2015
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Deciphering the Non-Equivalence of Serine and Threonine O-glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
Angewandte Chemie International, Vol. 54, Núm. 34, pp. 9830
2014
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Conformational analysis of peptides and glycopeptides derived from the consensus sequence for β-O-glucosylation
Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2712-2721
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Serine versus Threonine Glycosylation witha-O-GalNAc: Unexpected Selectivity in Their Molecular Recognition with Lectins
Chemistry - A European Journal, Vol. 20, Núm. 39, pp. 12616-12627
2011
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Engineering O-glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-associated Glycopeptides
Chemistry - A European Journal, Vol. 17, Núm. 11, pp. 3105-3110
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Rational design of a Tn antigen mimic
Chemical Communications, Vol. 47, Núm. 18, pp. 5319-5321
2007
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Serine versus Threonine Glycosylation: The Methyl Group Causes a Drastic Alteration on the Carbohydrate Orientation and on the Surrounding Water Shell
Journal of the American Chemical Society, Vol. 129, Núm. 30, pp. 9458-9467
2006
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Effect of beta-O-glucosylation on L-Ser and L-Thr Diamides: A Bias toward alfa-Helical Conformations
Chemistry - A European Journal, Vol. 12, Núm. 30, pp. 7864-7871
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New Insights into alfa-GalNAc-Ser Motif: Influence of Hydrogen Bonding versus Solvent Interactions on the Preferred Conformation
Journal of the American Chemical Society, Vol. 128, Núm. 45, pp. 14640-14648