Publicaciones en colaboración con investigadores/as de Instituto de Química Orgánica General (12)

2019

  1. Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

    Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072

2018

  1. Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition

    Journal of the American Chemical Society, Vol. 140, Núm. 31, pp. 9952-9960

2017

  1. The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer

    Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18255-18261

2016

  1. Mucin Architecture behind the Immune Response: Design and Evaluation of an Antitumor Vaccine Derived from an Unnatural MUC1 Fragment

    Chemical Science, Vol. 7, Núm. 3, pp. 2294

2015

  1. Deciphering the Non-Equivalence of Serine and Threonine O-glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

    Angewandte Chemie International, Vol. 54, Núm. 34, pp. 9830

2014

  1. Conformational analysis of peptides and glycopeptides derived from the consensus sequence for β-O-glucosylation

    Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2712-2721

  2. Serine versus Threonine Glycosylation witha-O-GalNAc: Unexpected Selectivity in Their Molecular Recognition with Lectins

    Chemistry - A European Journal, Vol. 20, Núm. 39, pp. 12616-12627

2011

  1. Engineering O-glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-associated Glycopeptides

    Chemistry - A European Journal, Vol. 17, Núm. 11, pp. 3105-3110

  2. Rational design of a Tn antigen mimic

    Chemical Communications, Vol. 47, Núm. 18, pp. 5319-5321

2007

  1. Serine versus Threonine Glycosylation: The Methyl Group Causes a Drastic Alteration on the Carbohydrate Orientation and on the Surrounding Water Shell

    Journal of the American Chemical Society, Vol. 129, Núm. 30, pp. 9458-9467

2006

  1. Effect of beta-O-glucosylation on L-Ser and L-Thr Diamides: A Bias toward alfa-Helical Conformations

    Chemistry - A European Journal, Vol. 12, Núm. 30, pp. 7864-7871

  2. New Insights into alfa-GalNAc-Ser Motif: Influence of Hydrogen Bonding versus Solvent Interactions on the Preferred Conformation

    Journal of the American Chemical Society, Vol. 128, Núm. 45, pp. 14640-14648