PROYECTOS I+D
Projecte CTQ2015-70524-R RETOS 2015
Una metodología computacional multi-escala para la modificación selectiva de proteínas y la reprogamación de enzimas.
D'àmbit Nacional.
Investigadors/es
Publicacions relacionades amb el projecte (19)
Mostra per tipologia2019
2018
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Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1- S- and C1- O-Nucleophiles
Journal of Organic Chemistry
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Cell-Penetrating Peptides Containing Fluorescent d-Cysteines
Chemistry - A European Journal
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Chemo- and Regioselective Lysine Modification on Native Proteins
Journal of the American Chemical Society
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Oxygen by Carbon Replacement at the Glycosidic Linkage Modulates the Sugar Conformation in Tn Antigen Mimics
ACS Omega
2017
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A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst
Journal of the American Chemical Society
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Metal-Free [2 + 2]-Photocycloaddition of (Z)-4-Aryliden-5(4H)-Oxazolones as Straightforward Synthesis of 1,3-Diaminotruxillic Acid Precursors: Synthetic Scope and Mechanistic Studies
ACS Sustainable Chemistry and Engineering
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Multiple Mechanisms for the Thermal Decomposition of Metallaisoxazolin-5-ones from Computational Investigations
Journal of Organic Chemistry
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1,3-Dipolar Cycloaddition Reactions of Low-Valent Rhodium and Iridium Complexes with Arylnitrile N-Oxides
Journal of Organic Chemistry
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Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
Angewandte Chemie International
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Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation
Journal of the American Chemical Society
2016
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Tn Antigen Mimics Based on sp2-Iminosugars with Affinity for an anti-MUC1 Antibody
Organic Letters
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Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition
Organic Letters
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Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders
Journal of the American Chemical Society
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A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2
Nature Chemical Biology
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Computations Reveal That Electron-Withdrawing Leaving Groups Facilitate Intramolecular Conjugate Displacement Reactions by Negative Hyperconjugation
Journal of Organic Chemistry
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Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
Nature Communications
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A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
Angewandte Chemie International