Publicacións en colaboración con investigadores/as de Universidad de Zaragoza (26)

2024

  1. Detection of Tumor-Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes

    Angewandte Chemie - International Edition, Vol. 63, Núm. 37

2023

  1. Methyl-to-Ethyl Replacement Makes the Difference: Structure-Guided Design of a New Cancer Vaccine Based on a Tn An-gen Surrogate

    VI RSEQ Chemical Biology Group Meeting - ChemBio VI

2022

  1. Aplicación de la Realidad Aumentada a la Visualización de Estructuras y de Procesos en Química Orgánica

    Aplicación de la Realidad Aumentada a la Visualización de Estructuras y de Procesos en Química Orgánica

2020

  1. Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment

    Chemical Science, Vol. 11, Núm. 15, pp. 3996-4006

2019

  1. Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

    Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072

2018

  1. The use of fluoroproline in MUC1 antigen enables efficient detection of antibodies inpatients with cancer

    29th International Carbohydrate Symposium - ICS2018

  2. Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition

    Journal of the American Chemical Society, Vol. 140, Núm. 31, pp. 9952-9960

2017

  1. The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer

    Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18255-18261

2016

  1. Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition

    Organic Letters, Vol. 18, Núm. 12, pp. 2796-2799

  2. Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety

    Journal of Organic Chemistry, Vol. 81, Núm. 14, pp. 5929-5941

  3. Mucin Architecture behind the Immune Response: Design and Evaluation of an Antitumor Vaccine Derived from an Unnatural MUC1 Fragment

    Chemical Science, Vol. 7, Núm. 3, pp. 2294

  4. Tn Antigen Mimics Based on sp2-Iminosugars with Affinity for an anti-MUC1 Antibody

    Organic Letters, Vol. 18, Núm. 15, pp. 3890-3893

2015

  1. Deciphering the Non-Equivalence of Serine and Threonine O-glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

    Angewandte Chemie International, Vol. 54, Núm. 34, pp. 9830

2014

  1. Serine versus Threonine Glycosylation witha-O-GalNAc: Unexpected Selectivity in Their Molecular Recognition with Lectins

    Chemistry - A European Journal, Vol. 20, Núm. 39, pp. 12616-12627

2002

  1. Preparation and Synthetic Applications of (S)- and (R)-N-Boc-N,O-Isopropylidene-alfa-methylserinals

    Targets in Heterocyclic Systems (ITALIAN SOCIETY OF CHEMISTRY), pp. 231-244

  2. Tandem Diels-Alder Cycloaddition/Rearrangement: a Method for the Synthesis of a 2,5,6-Trisubstituted Biphenyl

    Afinidad: Revista de química teórica y aplicada, Vol. 59, Núm. 500, pp. 431-434

1999

  1. Preparation and synthetic applications of (S)- and (R)-N-Boc-N,O-isopropylidene-alfa-methylserinals: asymmetric synthesis of (S)- and (R)-2-amino-2-methylbutanoic acids (Iva)

    Journal of Organic Chemistry, Vol. 64, Núm. 22, pp. 8220-8225

1998

  1. Synthesis of the four (d,l)-pairs of 4-hydroxy-2-phenylcyclohexane-alpha-amino acids: a new family of constrained hydroxyphenylalanines

    ANALES DE QUIMICA-INTERNATIONAL EDITION, Vol. 94, Núm. 1, pp. 50-55

1995

  1. Synthesis of a new constrained homoserine

    Synlett, Vol. 1995, Núm. 9, pp. 891-892

1991

  1. Development of a model to explain the influence of the solvent on the rate and selectivity of Diels-Alder reactions

    Journal of physical Organic Chemistry, Vol. 4, Núm. 1, pp. 48-52