Francisco
Corzana López
CATEDRÁTICO DE UNIVERSIDAD
Agatha
Bastida Codina
Publicacións nas que colabora con Agatha Bastida Codina (19)
2021
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De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot
Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 27, Núm. 20, pp. 6204-6212
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De Novo Design of Selective Quadruplex–Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot
Chemistry - A European Journal
2017
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A dynamic combinatorial chemistry approach to quantify the contribution of electrostatics to the stability of CH/Π bonds in water
19th European Carbohydrate Symposium
2016
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Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders
Journal of the American Chemical Society, Vol. 138, Núm. 20, pp. 6463-6474
2015
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A thorough experimental study of CH/π interactions in water: quantitative structure-stability relationships for carbohydrate/aromatic complexes
Chemical Science, Vol. 6, Núm. 11, pp. 6076-6085
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Modulating weak interactions for molecular recognition: A dynamic combinatorial analysis for assessing the contribution of electrostatics to the stability of CH-π bonds in water
Angewandte Chemie International, Vol. 54, Núm. 14, pp. 4344-4348
2014
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Chemical interrogation of drug/RNA complexes: from chemical reactivity to drug design
XI Carbohydrate Symposium
2013
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Chemical interrogation of drug/RNA complexes: From chemical reactivity to drug design
Angewandte Chemie International, Vol. 52, Núm. 11, pp. 3148-3151
2012
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Multiple Keys for a Single Lock: The Unusual Structural Plasticity of the Nucleotidyltransferase (4 ')/Kanamycin Complex
Chemistry - A European Journal, Vol. 18, Núm. 10, pp. 2875-2889
2010
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Role of Aromatic Rings in the Molecular Recognition of Aminoglycoside Antibiotics: Implications for Drug Design
Journal of the American Chemical Society, Vol. 132, Núm. 34, pp. 12074-12090
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Structural-based Design of Highly Crowded Ribostamycin/Kanamycin Hybrids as a new Family of Antibiotics
Chemistry - A European Journal, Vol. 16, Núm. 10, pp. 2986-2991
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The Unusual Nucleotide Recognition Properties of the Resistance Enzyme ANT(4 '): Inorganic Tri/Polyphosphate as a Substrate for Aminoglycoside Inactivation
Chemistry - A European Journal, Vol. 16, Núm. 29, pp. 8635-8640
2009
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Role of conserved Salt bridges in homeodomain stability and DNA binding
Journal of Biological Chemistry (Print), Vol. 284, Núm. 35, pp. 23765-23779
2008
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NMR-Based Analysis of Aminoglycoside Recognition by the Resistance Enzyme ANT(4′): The Pattern of OH/NH3+ Substitution Determines the Preferred Antibiotic Binding Mode and is Critical for Drug Inactivation
Journal of the American Chemical Society, Vol. 130, Núm. 15, pp. 5086-5103
2007
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A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition. Dramatic alterations in neomycin-B protonation state upon binding to a 23-mer RNA aptamer
Chemical Communications, Vol. 2, Núm. 2, pp. 174-176
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The Pattern of Distribution of Amino Groups Modulates the Structure and Dynamics of Natural Aminoglycosides: Implications for RNA Recognition
Journal of the American Chemical Society, Vol. 129, Núm. 10, pp. 2849-2865
2006
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Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance
Journal of the American Chemical Society, Vol. 128, Núm. 1, pp. 100-116
2005
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A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4
Journal of the American Chemical Society, Vol. 127, Núm. 23, pp. 8278-8279
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Molecular recognition of aminoglycoside antibiotics by bacterial defense proteins: NMR study of the structural and conformational features of streptomycin inactivation by bacillus subtilis Aminoglycoside-6-adenyl Transferase
Chemistry - A European Journal, Vol. 11, Núm. 17, pp. 5102-5113