Ramón Hurtado Guerrero-rekin lankidetzan egindako argitalpenak (18)

2024

  1. Design of glycopeptides for pancreatic cancer detection

    7th Iberian Carbohydrate Meeting: Abstract book

  2. Detection of Tumor-Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes

    Angewandte Chemie - International Edition, Vol. 63, Núm. 37

  3. Identification of Tumor-Linked Pancreatic Cancer Autoantibodies in Patients’ sera Through Engineered Glycopeptides

    XXIX RSEQ Biennial Meeting in Organic Chemistry: Santa Cruz de Tenerife, June 26-28, 2024: Abstract Book

  4. Structure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses

    JACS Au, Vol. 4, Núm. 1, pp. 150-163

2020

  1. Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment

    Chemical Science, Vol. 11, Núm. 15, pp. 3996-4006

2019

  1. Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

    Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072

2018

  1. The use of fluoroproline in MUC1 antigen enables efficient detection of antibodies inpatients with cancer

    29th International Carbohydrate Symposium - ICS2018

  2. Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition

    Journal of the American Chemical Society, Vol. 140, Núm. 31, pp. 9952-9960

2017

  1. The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer

    Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18255-18261

  2. The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

    Nature Communications, Vol. 8, Núm. 1

2016

  1. Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety

    Journal of Organic Chemistry, Vol. 81, Núm. 14, pp. 5929-5941

  2. Mucin Architecture behind the Immune Response: Design and Evaluation of an Antitumor Vaccine Derived from an Unnatural MUC1 Fragment

    Chemical Science, Vol. 7, Núm. 3, pp. 2294

2015

  1. Deciphering the Non-Equivalence of Serine and Threonine O-glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

    Angewandte Chemie International, Vol. 54, Núm. 34, pp. 9830

  2. Detection of tumor-associated glycopeptides by Lectins: The peptide context modulates carbohydrate recognition

    ACS chemical biology, Vol. 10, Núm. 3, pp. 747-756

  3. Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation

    Nature Communications, Vol. 6, pp. 1-12

2014

  1. Combined structural snapshots and metadynamics reveal a substrate-guided SNi-type reaction for polypeptide GalNAc transferaseT2

    XI Carbohydrate Symposium

  2. Serine versus Threonine Glycosylation witha-O-GalNAc: Unexpected Selectivity in Their Molecular Recognition with Lectins

    Chemistry - A European Journal, Vol. 20, Núm. 39, pp. 12616-12627

  3. Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2

    Angewandte Chemie International, Vol. 53, Núm. 31, pp. 8206-8210