Neurocognitive Functioning in Adolescents at Risk for Mental Health Problems

  1. Rebeca Aritio-Solana 1
  2. Eduardo Fonseca-Pedrero 1
  3. Alicia Pérez-Albéniz 2
  4. Oliver Mason 1
  5. Javier Ortuño-Sierra 1
  1. 1 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

  2. 2 Surrey University
Journal:
Psicothema

ISSN: 0214-9915,  1886-144X

Year of publication: 2022

Volume: 34

Issue: 2

Pages: 259-265

Type: Article

DOI: 10.7334/PSICOTHEMA2021.405 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Psicothema

Institutional repository: lock_openOpen access Editor

Abstract

Background: The main goal of the study was to assess the neurocognitive performance in adolescents at high psychometric risk for mental health problems. Method: A sample of 48 participants at high risk for mental disorders and an age-gender matched healthy comparison group of 48 adolescents were identified from a community-derived sample of 1,509 adolescents. The Strengths and Difficulties Questionnaire problems and the University of Pennsylvania Computerized Neuropsychological Test Battery for children (included 14 tasks assessing five neurobehavioral domains: executive functions, episodic memory, complex cognition, social cognition, and sensorimotor speed) were used. Results: Relative to healthy comparison participants, individuals at high risk showed significant impairments across almost all neurocognitive domains (executive functions, episodic memory, complex cognition, social cognition, and sensorimotor speed). Conclusions: These findings demonstrate that neurocognitive impairments can be shown in adolescents at high psychometric risk for mental health problems before the onset of more severe psychological problems

Bibliographic References

  • Agerup, T., Lydersen, S., Wallander, J., & Sund, A. M. (2015). Associations Between Parental Attachment and Course of Depression Between Adolescence and Young Adulthood. Child Psychiatry and Human Development, 46(4), 632-642. https://doi.org/10.1007/s10578-014- 0506-y
  • Basten, M. M. G. J., Althoff, R. R., Tiemeier, H., Jaddoe, V. W. V., Hofman, A., Hudziak, J. J., Verhulst, F. C., & van der Ende, J. (2013). The Dysregulation Profile in Young Children: Empirically Defined Classes in the Generation R Study. Journal of the American Academy of Child & Adolescent Psychiatry, 52(8), 841-850.e2. https://doi.org/10.1016/j. jaac.2013.05.007
  • Blakemore, S.-J., & Robbins, T. W. (2012). Decision-making in the adolescent brain. Nature Neuroscience, 15(9), 1184-1191. https://doi.org/10.1038/nn.3177
  • Blanken, L. M. E., White, T., Mous, S. E., Basten, M., Muetzel, R. L., Jaddoe, V. W. V., Wals, M., van der Ende, J., Verhulst, F. C., & Tiemeier, H. (2017). Cognitive functioning in children with internalising, externalising and dysregulation problems: A population-based study. European Child & Adolescent Psychiatry, 26(4), 445-456. https://doi.org/10.1007/s00787-016-0903-9
  • Calkins, M. E., Merikangas, K. R., Moore, T. M., Burstein, M., Behr, M. A., Satterthwaite, T. D., Ruparel, K., Wolf, D. H., Roalf, D. R., Mentch, F. D., Qiu, H., Chiavacci, R., Connolly, J. J., Sleiman, P. M. A., Gur, R. C., Hakonarson, H., & Gur, R. E. (2015). The Philadelphia Neurodevelopmental Cohort: Constructing a deep phenotyping collaborative. Journal of Child Psychology and Psychiatry and Allied Disciplines, 56(12), 1356-1369. https://doi.org/10.1111/jcpp.12416
  • Caspi, A., Houts, R. M., Ambler, A., Danese, A., Elliott, M. L., Hariri, A., Harrington, H. L., Hogan, S., Poulton, R., Ramrakha, S., Rasmussen, L. J. H., Reuben, A., Richmond-Rakerd, L., Sugden, K., Wertz, J., Williams, B. S., & Moffitt, T. E. (2020). Longitudinal Assessment of Mental Health Disorders and Comorbidities Across 4 Decades Among Participants in the Dunedin Birth Cohort Study. JAMA Network Open, 3(4), e203221. https://doi.org/10.1001/JAMANETWORKOPEN.2020.3221
  • Cotter, J. (2018). Social cognitive dysfunction as a clinical marker: A systematic review of meta-analyses across 30 clinical conditions. Neuroscience Biobehavioral Review, 84, 92-99.
  • Drabick, D. A. G., & Kendall, P. C. (2010). Developmental Psychopathology and the Diagnosis of Mental Health Problems among Youth. Clinical Psychology: A Publication of the Division of Clinical Psychology of the American Psychological Association, 17(4), 272-280. https://doi.org/10.1111/j.1468-2850.2010.01219.x
  • Dray, J., Bowman, J., Campbell, E., Freund, M., Wolfenden, L., Hodder, R. K., McElwaine, K., Tremain, D., Bartlem, K., Bailey, J., Small, T., Palazzi, K., Oldmeadow, C., & Wiggers, J. (2017). Systematic Review of Universal Resilience-Focused Interventions Targeting Child and Adolescent Mental Health in the School Setting. Journal of the American Academy of Child & Adolescent Psychiatry, 56(10), 813-824. https://doi.org/10.1016/j.jaac.2017.07.780
  • Fonseca-Pedrero, E. (2021). Manual de tratamientos psicológicos Infancia y adolescencia [Manual of psychological treatments Childhood and adolescence]. Pirámide.
  • Fonseca-Pedrero, E., Debbané, M., Rodríguez-Testal, J. F., Cohen, A. S., Docherty, A. R., & Ortuño-Sierra, J. (2021). Schizotypy: The way ahead. Psicothema, 33(1), 16-27 https://doi.org/10.7334/psicothema2019.285
  • Fonseca-Pedrero, E., Inchausti, F., Pérez-Gutiérrez, L., Aritio Solana, R., Ortuño-Sierra, J., Sánchez-García, M. Á., Lucas-Molina, B., Domínguez, C., Foncea, D., Espinosa, V., Gorría, A., Urbiola-Merina, E., Fernández, M., Merina Díaz, C., Gutiérrez, C., Aures, M., Campos, M. S., Domínguez-Garrido, E., & Pérez de Albéniz Iturriaga, A. (2017). Suicidal ideation in a community-derived sample of Spanish adolescents. Revista de Psiquiatria y Salud Mental, 11(2), 76-85. https://doi.org/10.1016/j.rpsm.2017.07.004
  • Fonseca-Pedrero, E., Paino-Piñeiro, M., Lemos-Giráldez, S., Villazón-García, U., & Muñiz, J. (2009). Validation of the Schizotypal Personality Questionnaire-Brief Form in adolescents. Schizophrenia Research, 111(1-3), 53-60. https://doi.org/10.1016/j.schres.2009.03.006
  • Fonseca-Pedrero, E., Pérez-Álvarez, M., Al-Halabí, S., Inchausti, F., López-Navarro, E. R., Muñiz, J., Lucas-Molina, B., Pérez-Albéniz, A., Baños Rivera, R., Cano-Vindel, A., Gimeno-Peón, A., Prado-Abril, J., González-Menéndez, A., Valero, A. V, Priede, A., González-Blanch, C., Ruiz-Rodríguez, P., Moriana, J. A., Gómez, L. E., … Montoya-Castilla, I. (2021). Empirically supported psychological treatments for children and adolescents: State of the art. Psicothema, 33(3), 386-398. https://doi.org/10.7334/PSICOTHEMA2021.56
  • Fusar-Poli, P., Deste, G., Smieskova, R., Barlati, S., Yung, A. R., Howes, O., Stieglitz, R.-D., Vita, A., McGuire, P., & Borgwardt, S. (2012). Cognitive Functioning in Prodromal Psychosis. Archives of General Psychiatry, 69(6), 562-571. https://doi.org/10.1001/archgenpsychiatry.2011.1592
  • Gottesman, I. I., & Gould, T. D. (2003). The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions. American Journal of Psychiatry, 160(4), 636-645. https://doi.org/10.1176/appi. ajp.160.4.636
  • Gur, R. C., Calkins, M. E., Satterthwaite, T. D., Ruparel, K., Bilker, W. B., Moore, T. M., Savitt, A. P., Hakonarson, H., & Gur, R. E. (2014). Neurocognitive Growth Charting in Psychosis Spectrum Youths. JAMA Psychiatry, 71(4), 366. https://doi.org/10.1001/ jamapsychiatry.2013.4190
  • Gur, R. C., Richard, J., Calkins, M. E., Chiavacci, R., Hansen, J. A., Bilker, W. B., Loughead, J., Connolly, J. J., Qiu, H., Mentch, F. D., Abou-Sleiman, P. M., Hakonarson, H., & Gur, R. E. (2012). Age group and sex differences in performance on a computerized neurocognitive battery in children age 8-21. Neuropsychology, 26(2), 251-265. https://doi.org/10.1037/A0026712
  • Gur, R. C., Richard, J., Hughett, P., Calkins, M. E., Macy, L., Bilker, W. B., Brensinger, C., & Gur, R. E. (2010). A cognitive neurosciencebased computerized battery for efficient measurement of individual differences: Standardization and initial construct validation. Journal of Neuroscience Methods, 187(2), 254-262. https://doi.org/10.1016/j. jneumeth.2009.11.017
  • Hobson, C. W., Scott, S., & Rubia, K. (2011). Investigation of cool and hot executive function in ODD/CD independently of ADHD. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 52(10), 1035- 1043. https://doi.org/10.1111/j.1469-7610.2011.02454.x
  • IBM Corp Released (2013). IBM SPSS Statistics for Windows, Version 22.0. IBM Corp.
  • Loge, D. V., Staton, R. D., & Beatty, W. W. (1990). Performance of Children with ADHD on Tests Sensitive to Frontal Lobe Dysfunction. Journal of the American Academy of Child & Adolescent Psychiatry, 29(4), 540- 545. https://doi.org/10.1097/00004583-199007000-00006
  • McGrath, J. J., Saha, S., Al-Hamzawi, A. O., Alonso, J., Andrade, L., Borges, G., Bromet, E. J., Browne, M. O., Bruffaerts, R., Caldas De Almeida, J. M., Fayyad, J., Florescu, S., De Girolamo, G., Gureje, O., Hu, C., De Jonge, P., Kovess-Masfety, V., Lepine, J. P., Lim, C. C. W., … Kessler, R. C. (2016). Age of onset and lifetime projected risk of psychotic experiences: Cross-national data from the world mental health survey. Schizophrenia Bulletin, 42(4), 933-941. https://doi.org/10.1093/schbul/sbw011
  • McQuade, J. D., Murray-Close, D., Shoulberg, E. K., & Hoza, B. (2013). Working memory and social functioning in children. Journal of Experimental Child Psychology, 115(3), 422-435. https://doi.org/10.1016/j.jecp.2013.03.002
  • Merikangas, A. K., Cui, L., Calkins, M. E., Moore, T. M., Gur, R. C., Gur, R. E., & Merikangas, K. R. (2017). Neurocognitive performance as an endophenotype for mood disorder subgroups. Journal of Affective Disorders, 215, 163-171. https://doi.org/10.1016/j.jad.2017.03.021
  • Mewton, L., Hodge, A., Gates, N., Visontay, R., & Teesson, M. (2017). The Brain Games study: protocol for a randomised controlled trial of computerised cognitive training for preventing mental illness in adolescents with high-risk personality styles. BMJ Open, 7(9), e017721. https://doi.org/10.1136/bmjopen-2017-017721
  • Moore, T. M., Gur, R. C., Thomas, M. L., Brown, G. G., Nock, M. K., Savitt, A. P., Keilp, J. G., Heeringa, S., Ursano, R. J., & Stein, M. B. (2017). Development, Administration, and Structural Validity of a Brief, Computerized Neurocognitive Battery. Assessment, 107319111668982. https://doi.org/10.1177/1073191116689820
  • Moore, T. M., Reise, S. P., Gur, R. E., Hakonarson, H., & Gur, R. C. (2015). Psychometric properties of the Penn Computerized Neurocognitive Battery. Neuropsychology, 29(2), 235-246. https://doi.org/10.1037/ neu0000093
  • Muñiz, J., Elosua, P., & Hambleton, R. K. (2013). Directrices para la traducción y adaptación de los tests: segunda edición [International Test Commission Guidelines for test translation and adaptation: Second edition]. Psicothema, 25(2), 151-157. https://doi.org/10.7334/ psicothema2013.24
  • Ortuño-Sierra, J., Fonseca-Pedrero, E., Paino, M., Sastre I Riba, S., & Muñiz, J. (2015). Screening mental health problems during adolescence: Psychometric properties of the Spanish version of the strengths and difficulties Questionnaire. Journal of Adolescence, 38(2), 49-56. https://doi.org/10.1016/j.adolescence.2014.11.001
  • Polanczyk, G. V., Fatori, D., & Matijasevich, A. (2018). Integrating child and adolescent psychiatry and the field of early childhood development. European Child & Adolescent Psychiatry, 27(2), 137-138. https://doi.org/10.1007/s00787-018-1131-2
  • Polanczyk, G. V., Salum, G. A., Sugaya, L. S., Caye, A., & Rohde, L. A. (2015). Annual research review: A meta-analysis of the worldwide prevalence of mental disorders in children and adolescents. Journal of Child Psychology and Psychiatry, 56, 345-365.
  • Santamaría-García, H., Baez, S., Gómez, C., Rodríguez-Villagra, O., Huepe, D., Portela, M., Reyes, P., Klahr, J., Matallana, D., & Ibanez, A. (2020). The role of social cognition skills and social determinants of health in predicting symptoms of mental illness. Translational Psychiatry, 10(1), 1-13. https://doi.org/10.1038/s41398-020-0852-4
  • Schoemaker, K., Bunte, T., Espy, K. A., Deković, M., & Matthys, W. (2014). Executive functions in preschool children with ADHD and DBD: An 18-month longitudinal study. Developmental Neuropsychology, 39(4), 302-315. https://doi.org/10.1080/87565641.2014.911875
  • Schoemaker, M. M., Niemeijer, A. S., Flapper, B. C. T., & Smits-Engelsman, B. C. M. (2012). Validity and reliability of the Movement Assessment Battery for Children-2 Checklist for children with and without motor impairments. Developmental Medicine and Child Neurology, 54(4), 368-375. https://doi.org/10.1111/j.1469-8749.2012.04226.x
  • Spear, L. P. (2013). Adolescent neurodevelopment. The Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine, 52(2 Suppl 2), S7-13. https://doi.org/10.1016/j.jadohealth.2012.05.006
Data source: Dialnet