ESBL, plasmidic AmpC, and associated quinolone resistance determinants in coliforms isolated from hospital effluent: First report of qnrB2, qnrB9, qnrB19, and blaCMY-4 in Algeria
- Anssour, L. 2
- Messai, Y. 2
- Derkaoui, M. 2
- Alouache, S. 23
- Estepa, V. 1
- Somalo, S. 1
- Torres, C. 1
- Bakour, R. 2
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1
Universidad de La Rioja
info
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2
University of Sciences and Technology Houari Boumediene
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University of Sciences and Technology Houari Boumediene
Argel, Argelia
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3
École Nationale Supérieure des Sciences de la Mer et de l'Aménagement du Littoral
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École Nationale Supérieure des Sciences de la Mer et de l'Aménagement du Littoral
Argel, Argelia
ISSN: 1120-009X
Argitalpen urtea: 2014
Alea: 26
Zenbakia: 2
Orrialdeak: 74-79
Mota: Artikulua
beta Ver similares en nube de resultadosBeste argitalpen batzuk: Journal of Chemotherapy
Lotura duten proiektuak
Laburpena
The characterization of extended-spectrum beta-lactamases, plasmidic AmpC (pAmpC), and associated plasmid-mediated quinolone resistance (PMQR) determinants in cefotaxime-resistant coliforms isolated from hospital effluent in Algiers showed bla CTX-M genes in 89%, bla TEM-1 in 79•8%, and pAmpC genes (bla CIT) in 2•7% isolates. Association of IS Ecp1B with bla CTX-M was found in all CTX-M+ isolates, and 97•2% harboured class 1 integrons. Sequencing showed bla CTX-M-15, bla CTX-M-3, and bla CMY-4 genes. bla CTX-M-3 and bla CTX-M-15 were located in Inc L/M conjugative plasmids. The PMQR determinants identified were qnrB1, qnrB2, qnrB9, qnrB19, qnrS2, and aac(6')-Ib-cr. qnrB2, qnrB9, qnrB19, and bla CMY-4are described for the first time in Algeria and qnrB19 for the first time in non-clinical environments. This study highlights the major potential role of hospital effluents as providers of resistance genes to natural environments. © 2014 Edizioni Scientifiche per l'Informazione su Farmaci e Terapia.