Mechanistic Study of the Ring-Size Modulation in Michael-Dieckmann type Reactions of 2-Acylaminoacrylates with Ketene Diethyl Acetal
- Avenoza, A. 1
- Busto, J.H. 1
- Canal, N. 1
- García, J.I. 2
- Jiménez-Osés, G. 1
- Peregrina, J.M. 1
- Pérez-Fernández, M. 1
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1
Universidad de La Rioja
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2
Instituto de Nanociencia y Materiales de Aragón
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ISSN: 1144-0546
Año de publicación: 2007
Volumen: 31
Número: 2
Páginas: 224-229
Tipo: Artículo
beta Ver similares en nube de resultadosOtras publicaciones en: New Journal of Chemistry
Resumen
An unexpected modulation of the chemoselectivity in the Michael-Dieckmann type reactions of 2-acylaminoacrylates with ketene diethyl acetal is observed, depending on the nature of the acylamino group. Experimental and theoretical studies are presented to offer insights into the origin of this substituent effect in terms of a polar stepwise mechanism. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.