Diastereoselective Synthesis of Protected 4-epi-Vancosamine from (S)-N-Boc-N,O-isopropylidene-alfa-methylserinal
- Avenoza, A. 1
- Busto, J.H. 1
- Corzana, F. 1
- Peregrina, J.M. 1
- Sucunza, D. 1
- Zurbano, M.M. 1
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1
Universidad de La Rioja
info
ISSN: 0957-4166
Année de publication: 2003
Volumen: 14
Número: 8
Pages: 1037-1043
Type: Article
D'autres publications dans: Tetrahedron: Asymmetry
Résumé
An efficient diastereoselective synthesis of methyl N,O-dibenzoyl-L-4-epi-vancosamine is described. The key step involves Sharpless asymmetric dihydroxylation of a Z olefin derived from (S)-N-Boc-N,O-isopropylidene-α-methylserinal. © 2003 Elsevier Science Ltd. All rights reserved.