The use of 4-hetarylidene- and 4-arylidene-5(4H)-oxazolones as dienophiles. Appropriate reagents to synthesize cyclic analogues of natural amino acids
- Avenoza, A. 1
- Busto, J.H. 1
- París, M. 1
- Peregrina, J.M. 1
- Cativiela, C. 2
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1
Universidad de La Rioja
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2
Instituto de Nanociencia y Materiales de Aragón
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ISSN: 0022-152X
Année de publication: 1997
Volumen: 34
Número: 4
Pages: 1099-1110
Type: Article
D'autres publications dans: Journal of Heterocyclic Chemistry
Résumé
This report describes the behavior of 4-hetaryliden- and 4-aryliden-5(4H)-oxazolones as dienophiles in the Diels-Alder reaction with several dienes. The application of this reaction to the synthesis of different conformationally constrained cyclic analogues of natural amino acids of pharmacological interest is also described.