Synthesis of a new enantiomerically pure constrained homoserine
- Avenoza, A. 1
- Cativiela, C. 2
- Fernández-Recio, M.A. 1
- Peregrina, J.M. 1
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1
Universidad de La Rioja
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2
Instituto de Nanociencia y Materiales de Aragón
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ISSN: 0957-4166
Year of publication: 1996
Volume: 7
Issue: 3
Pages: 721-728
Type: Article
beta Ver similares en nube de resultadosMore publications in: Tetrahedron: Asymmetry
Abstract
The use of the Diels-Alder reaction between 1,3-butadiene and chiral 2-acetamidoacrylates as the key step followed by stereocontrolled transformations allows the synthesis of (1S,3R)-1-amino-3-hydroxycyclohexanecarboxylic acid, a new type of constrained homoserine, with an excellent overall yield.