Synthesis of exo-2-phenyl-7-azabicyclo[2.2.1.]heptane-1-carboxylic acid: A new constrained proline analogue
- Avenoza, A. 1
- Cativiela, C. 2
- Busto, J.H. 1
- Peregrina, J.M. 1
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1
Universidad de La Rioja
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2
Instituto de Nanociencia y Materiales de Aragón
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ISSN: 0040-4039
Year of publication: 1995
Volume: 36
Issue: 39
Pages: 7123-7126
Type: Article
More publications in: Tetrahedron Letters
Abstract
A synthetic route to exo-2-phenyl-7-azabicyclo[2.2.1]heptane-1-carboxylic acid (a constrained proline analogue) in which the key step is the Diels-Alder reaction between (Z)-2-phenyl-4-benzylidene-5(4H)-oxazolone and Danishefsky's diene is described.