A new efficient synthesis of 2-phenyl-4-oxo-1-aminocyclohexanecarboxylic acids
- Avenoza, A. 2
- Busto, J.H. 2
- Cativiela, C. 1
- Peregrina, J.M. 2
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1
Instituto de Nanociencia y Materiales de Aragón
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2
Universidad de La Rioja
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ISSN: 0040-4020
Year of publication: 1994
Volume: 50
Issue: 45
Pages: 12989-12998
Type: Article
More publications in: Tetrahedron
Abstract
The adducts obtained through the Diels-Alder cycloadditions of (Z)-2-phenyl-4-benzyliden-5(4H)-oxazolone 1 with Danishefsky's diene and of methyl (E)-2-cyanocinnamate 9 with 2-methoxy-1,3-butadiene, were subsequently transformed allowing the synthesis of both stereoisomers of 2-phenyl4-oxo-1-aminocyclohexanecarboxylic acid (8 and 20).