New Synthesis of Gold- and Silver-Based Nano-Tetracycline Composites
- Djafari, J. 11
- Marinho, C. 133
- Santos, T. 133
- Igrejas, G. 3
- Torres, C. 2
- Capelo, J.L. 1
- Poeta, P. 13
- Lodeiro, C. 11
- Fernández-Lodeiro, J. 11
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1
Universidade Nova de Lisboa
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2
Universidad de La Rioja
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3
Universidade de Trás-os-Montes e Alto Douro
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ISSN: 2191-1363
Year of publication: 2016
Volume: 5
Issue: 3
Pages: 206-212
Type: Article
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Abstract
A new synthetic methodology of water-soluble gold and silver nanoparticles (AuNPs@TC and AgNPs@TC), using the antibiotic tetracycline (TC) as co-reducing and stabilizing agent, is reported. Both colloids exhibit high water stability. The average sizes obtained were 25±10 and 15±5 nm, respectively. Both composites were tested against TC-resistant bacteria, presenting an increasing antibacterial effect in the case of AgNPs@TC. The sensing towards metal ions was also explored. An interesting and reversible affinity of AuNPs@TC towards AlIII cations in an aqueous system was also observed. © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.