Avances en la evaluación de los síntomas negativos en el síndrome psicótico

  1. Fonseca Pedrero, Eduardo 1
  2. Inchausti, Félix 2
  3. Ortuño Sierra, Javier 1
  4. Gutiérrez, Carmen 3
  5. Gooding, Diane C. 4
  6. Paino Piñeiro, María de las Mercedes 5
  1. 1 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

  2. 2 Centro Hospitalario Benito Menni de Elizondo, Spain
  3. 3 Unidad de Salud Mental, Hospital San Pedro, Spain
  4. 4 Universidad de Wisconsin-Madison, EEUU, Spain
  5. 5 Universidad de Oviedo
    info

    Universidad de Oviedo

    Oviedo, España

    ROR https://ror.org/006gksa02

Revista:
Papeles del psicólogo

ISSN: 0214-7823 1886-1415

Año de publicación: 2015

Volumen: 36

Número: 1

Páginas: 33-45

Tipo: Artículo

Otras publicaciones en: Papeles del psicólogo

Resumen

El presente trabajo tiene como objeto acercar al profesional de la psicología los últimos avances desarrollados en el campo de la evaluación de los síntomas negativos en los trastornos del espectro psicótico y condiciones relacionadas. En un primer lugar, se comenta brevemente el desarrollo histórico de los síntomas negativos, su conceptualización, y su impacto en la práctica clínica y la investigación. En segundo lugar, se mencionan los instrumentos disponibles para la evaluación de los síntomas negativos. Se focaliza el discurso en las herramientas de nueva construcción, y se mencionan sus características psicométricas. Asimismo, se señalan diferentes instrumentos de medida para la evaluación de los síntomas negativos como expresión de condición de riesgo o de vulnerabilidad a la psicosis, tanto dentro del paradigma de alto riesgo clínico como psicométrico. En tercer lugar, y para finalizar, se diserta a modo de recapitulación sobre algunas conclusiones, directrices y posibles desarrollos futuros en este área de estudio.

Referencias bibliográficas

  • Addington, J., Stowkowy, J., y Weiser, M. (2014). Screening tools for clinical high risk for psychosis. Early Intervention in Psychiatry, doi: 10.1111/eip.12193.
  • Alphs, L., Morlock, R., Coon, C., van Willigenburg, A., y Panagides, J. (2010). The 4-item negative symptom assessment (NSA-4) instrument: A simple tool for evaluating negative symptoms in schizophrenia following brief training. Psychiatry, 7, 26-32.
  • Álvarez-López, E. (2005). Personalidad esquizotípica y marcadores cognitivos. Tesis doctoral no publicada, Tesis doctoral no publicada. Universidad de Barcelona, Barcelona.
  • Andreasen, N. C. (1983). The Scale for the Assessment of Negative Symptoms (SANS). Iowa City, Iowa: The University of Iowa.
  • Axelrod, B. N., Goldman, R. S., y Alphs, L. D. (1993). Validation of the 16-item negative symptom assessment. Journal of Psychiatric Research, 27(3), 253-258.
  • Barch, D. M., Bustillo, J., Gaebel, W., Gur R., Heckers, S., Malaspina, D., . . . Carpenter W. (2013). Logic and justification for dimensional assessment of symptoms and related clinical phenomena in psychosis: Relevance to DSM-5. Schizophrenia Research, 150, 15-20.
  • Berridge, K., C,, , y Kringelbach, M. L. (2008). Affective neuroscience of pleasure: reward in humans and animals. Psychopharmacology (Berl), 199, 457-480.
  • Blanchard, J. J., y Cohen, A. S. (2006). The structure of negative symptoms within schizophrenia: implications for assessment. Schizophrenia Bulletin, 32(2), 238- 245.
  • Bleuler, E. (1911). Dementia praecox or the group of schizophrenias. New York: International Universities Press (Trad. 1950).
  • Bobes, J., Arango, C., Garcia-Garcia, M., Rejas, J., y CLAMORS Study Collaborative Group. (2010). Preva- lence of negative symptoms in outpatients with schizophrenia spectrum disorders treated with antipsychotics in routine clinical practice: findings from the CLAMORS study. Journal of Clinical Psychiatry, 71, 280-286.
  • Buckley, P. F., Miller, B. J., Lehrer, D. S., y Castle, D. J. (2009). Psychiatric comorbidities and schizophrenia. Schizophrenia Bulletin, 35, 383-402.
  • Buchanan, R. W. (2007). Persistent negative symptoms in schizophrenia: an overview. Schizophrenia Bulletin 33, 1013-1022.
  • Cascón, I. V., y García Medina, P. (1997). Propiedades psicométricas de las escalas de síntomas esquizofrénicos positivos y negativos de Andreasen. Psicología Conductual, 5, 93-108.
  • Cohen, A. S., Mitchell, K. R., y Elvevåg, B. (2014). What do we really know about blunted vocal affect and alogia? A meta-analysis of objective assessments. Schizophrenia Research, 159, 533-538.
  • Chapman, J. P., Chapman, L. J., y Raulin, M. L. (1976). Scales for physical and social anhedonia. Journal of Abnormal Psychology, 87, 374-382.
  • Daniel, D. G. (2013). Issues in selection of instruments to measure negative symptoms. Schizophrenia Research, 150, 343-345.
  • Docherty, A. R., y Sponheim, S. R. (2014). Anhedonia as an indicator of genetic vulnerability. En M. S. Ritsner (Ed.), Anhedonia: A comphrensive Handbook (vol. II) (Vol. II, pp. 105-123). New York: Springer.
  • Eckblad, M., Chapman, L. J., Chapman, J. P., y Mishlove, M. (1982). The Revised Social Anhedonia Scale.Unpublished manuscript, University of Wisconsin Madison.
  • Elis, O., Caponigro, J. M., y Kring, A. M. (2013). Psychosocial treatments for negative symptoms in schizophrenia: current practices and future directions. Clinical Psychology Review, 33, 914-928.
  • Ettinger, U., Meyhöfer, I., Steffens, M., Wagner, M., y Koutsouleris, N. (2014). Genetics, cognition, and neurobiology of schizotypal personality: a review of the
  • overlap with schizophrenia. Frontiers of Psychiatry, 5, 18.
  • Fonseca-Pedrero, E., Fumero, A., Paino, M., de Miguel, A., Ortuño-Sierra, J., Lemos Giraldez, S., y Muñiz, J. (2014). Schizotypal Personality Questionnaire: New sources of validity evidence in college students. Psychiatry Research, 219, 214-220.
  • Fonseca-Pedrero, E., Gooding, D. C., Paino, M., LemosGiráldez, S., y Muñiz, J. (2014). Measuring anhedonia in schizophrenia spectrum disordes: A selective update. En M. S. Ritsner (Ed.), Anhedonia: A Comprehensive handbook (pp. 19-54). New York: Springer.
  • Fonseca-Pedrero, E., Lemos-Giráldez, S., Paino, M., Santarén-Rosell, M., Sierra-Baigrie, S., y OrdóñezCamblor, N. (2011). Instrumentos de medida para la evaluación del fenotipo psicótico [Measuring instruments for evaluation phenotype of psychotic]. Papeles del Psicólogo, 32, 129-151.
  • Fonseca-Pedrero, E., Muñiz, J., Lemos-Giráldez, S., Paino, M., y Villazón-García, U. (2010). ESQUIZO-Q: Cuestionario Oviedo para la Evaluación de la Esqui- zotipia [ESQUIZO-Q: Oviedo Questionnaire for Schizotypy Assessment ]. Madrid: TEA ediciones.
  • Fonseca-Pedrero, E., Paino, M., Lemos-Giráldez, S., García-Cueto, E., Campillo-Álvarez, A., VillazónGarcía, U., y Muñiz, J. (2008). Schizotypy assessment: State of the art and future prospects. International Journal of Clinical and Health Psychology, 8, 577-593.
  • Fonseca-Pedrero, E., Paino, M., Lemos-Giráldez, S., y Muñiz, J. (2012). Validation of the Community Assessment Psychic Experiences -42 (CAPE-42) in Spanish college students and patients with psychosis. Actas Españolas de Psiquiatría, 40, 169-176.
  • Fonseca-Pedrero, E., Paino, M., Lemos-Giráldez, S., Sierra-Baigrie, S., y Muñiz, J. (2010). Factor structure and measurement invariance of the Wisconsin Schizotypy Scales across gender and age. Spanish Journal of Psychology, 13(2), 939-948.
  • Fonseca-Pedrero, E., Paino, M., Ortuño-Sierra, J., Lemos Giraldez, S., y Muñiz, J. (2013). Dimensionality of the Wisconsin Schizotypy Scales Brief forms in college students. The Scientific World Journal, (2013), Article ID 625247.
  • Fonseca Pedrero, E., Paino, M., y Fraguas, D. (2013). DSM-5: ¿Síndrome de psicosis atenuada? Papeles del Psicólogo, 34, 190-207.
  • Forbes, C., Blanchard, J. J., Bennett, M., Horan, W. P., Kring, A., y Gur, R. (2010). Initial development and
  • preliminary validation of a new negative symptom measure: The Clinical Assessment Interview for Negative Symptoms (CAINS). Schizophrenia Research, 124(1- 3), 36-42.
  • Fusar-Poli, P., Bonoldi, I., Yung, A. R., Borgwardt, S., Kempton, M. J., Valmaggia, L., . . . McGuire, P. (2012). Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk. Archives of General Psychiatry, 69, 220-229.
  • Fusar-Poli, P., Carpenter, W. T., Woods, S. W., y McGlashan, T. H. (2014). Attenuated Psychosis Syndrome: Ready for DSM-5.1? Annual Review of Clinical Psychology, 10, 155-192.
  • García-Portilla González, M. P., y Bobes, J. (2013). Ante el nuevo reto de identificar el síndrome negativo de la esquizofrenia. Revista de Psiquiatría y Salud Mental, 6, 141-143.
  • Gard, D. E., Gard, M. G., Kring, A. M., y John, O. P. (2006). Anticipatory and consummatory components of the experience of pleasure: A scale development study. Journal of Research in Personality, 40(6), 1086-1102.
  • Gard, D. E., Kring, A. M., Gard, M. G., Horan, W. P., y Green, M. F. (2007). Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure. Schizophrenia Research, 93, 253-260.
  • Gooding, D. C., Cohen, A. S., y Pflum, M. J. (2014). Hedonic capacity and schizotypy: Evidence for the criterion validity of the ACIPS. Comprehensive Psychiatry, 55, 1455-1461.
  • Gooding, D. C., y Pflum, M. J. (2014). The assessment of interpersonal pleasure: Introduction of the Anticipatory and Consummatory Interpersonal Pleasure Scale (ACIPS) and preliminary findings. Psychiatry Research, 215, 237-243.
  • Gooding, D. C., Tallent, K. A., y Matts, C. W. (2005). Clinical status of at-risk individuals 5 years later: Further validation of the psychometric high-risk strategy. Journal of Abnormal Psychology, 114(1), 170-175.
  • Gore, F. M., Bloem, P. J., Patton, G. C., Ferguson, J., Joseph, V., Coffey, C., . . . Mathers, C. D. (2011). Global burden of disease in young people aged 10-24 years: a systematic analysis. Lancet, 18(377), 2093- 2102.
  • Heckers, S., Barch, D. M., Bustillo, J., Gaebel, W., Gur, R., Malaspina, D., . . . Carpenter, W. (2013). Structure of the psychotic disorders classification in DSM 5. Schizophrenia Research, 150, 11-14.
  • Horan, W. P., Kring, A. M., y Blanchard, J. J. (2006). Anhedonia in schizophrenia: A review of assessment strategies. Schizophrenia Bulletin, 32, 259-273.
  • Anhedonia in schizophrenia: A review of assessment strategies. Schizophrenia Bulletin, 32, 259-273.
  • Horan, W. P., Kring, A. M., Gur, R. E., Reise, S. P., y Blanchard, J. J. (2011). Development and Psychometric Validation of the Clinical Assessment Interview for Negative Symptoms (CAINS). Schizophrenia Research, 132, 140-145.
  • Kane, J. M. (2013). Tools to assess negative symptoms in schizophrenia. Journal of Clinical Psychiatry, 74, e12. doi: 10.4088/JCP.12045tx12042c.
  • Kay, S. R., Fiszbein, A., y Opler, L. A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13, 261-276.
  • Kendler, K. S. (1985). Diagnostic approaches to schizotypal personality disorder: A historical perspective. Schizophrenia Bulletin, 11, 538-553.
  • Kirkpatrick, B., Fenton, W. S., Carpenter Jr, W. T., y Marder, S. R. (2006). The NIMH-MATRICS consensus statement on negative symptoms. Schizophrenia Bulletin, 32(2), 214-219.
  • Kirkpatrick, B., Strauss, G. P., Nguyen, L., Fischer, B. A., Daniel, D. G., Cienfuegos, A., y Marder, S. R. (2011). The brief negative symptom scale: Psychometric properties. Schizophrenia Bulletin, 37(2), 300-305.
  • Kline, E., y Schiffman, J. (2014). Psychosis risk screening: A systematic review. Schizophrenia Research, 158, 11-18.
  • Kring, A. M., Gur, R. E., Blanchard, J. J., Horan, W. P., y Reise, S. P. (2013). The Clinical Assessment Interview for Negative Symptoms (CAINS): Final development and validation. American Journal of Psychiatry, 170, 165-172.
  • Kwapil, T. R., Barrantes Vidal, N., y Silvia, P. J. (2008). The dimensional structure of the Wisconsin schizotypy scales: Factor identification and construct validity. Schizophrenia Bulletin, 34, 444-457.
  • Kwapil, T. R., Gross, G. M., Silvia, P. J., y Barrantes-Vidal, N. (2013). Prediction of psychopathology and functional impairment by positive and negative schizotypy in the Chapmans' ten-year longitudinal study. Journal of Abnormal Psychology, 122, 807-815.
  • Lemos Giraldez, S., Paino, M., y Fonseca Pedrero, E. y Vallina, O. (en prensa). Esquizofrenia y otros trastornos psicóticos. Madrid: Síntesis.
  • Lemos, S., Vallina, O., Fernández, P., Ortega, J. A., Garcia, P., Gutiérrez, A., . . . Miller, T. (2006). Validez predictiva de la Escala de Síntomas Prodrómicos (SOPS) / Predictive validity of the Scale of Prodromal Symptoms (SOPS). Actas Españolas de Psiquiatría, 34, 216-223.
  • Lenzenweger, M. F. (2010). Schizotypy and schizophrenia: The view from experimental psychopathology. New York: Guilford Press.
  • Leucht, S., Corves, C., Arbter, D., Engel, R. R., Li, C., y Davis, J. M. (2009). Second-generation versus firstgeneration antipsychotic drugs for schizophrenia: a meta-analysis. Lancet, 373, 31-41.
  • Lindenmayer, J. P., Harvey, P. D., Khan, A., y Kirkpatrick, B. (2007). Schizophrenia: measurements of psychopathology. Psychiatric Clinics of North America, 30, 339-363.
  • Linscott, R. J., y van Os, J. (2013). An updated and conservative systematic review and meta-analysis of epidemiological evidence on psychotic experiences in children and adults: on the pathway from proneness to persistence to dimensional expression across mental disorders. Psychological Medicine, 43, 1133-1149.
  • Llerena, K., Park, S. G., McCarthy, J. M., Couture, S. M., Bennett, M. E., y Blanchard, J. J. (2013). The Motivation and Pleasure Scale-Self-Report (MAP-SR): Reliability and validity of a self-report measure of negative symptoms. Comprehensive Psychiatry, 54, 568-574.
  • Mané, A., García-Rizo, C., García-Portilla, M. P., Bergé, D., Sugranyes, G., García-Alvarez, L., . . . Fernandez-Egea, E. (2014). Spanish adaptation and validation of the Brief Negative Symptoms Scale. Comprehensive Psychiatry, 55, 1726-1729.
  • Marder, S. R., y Kirkpatrick, B. (2014). Defining and measuring negative symptoms of schizophrenia in clinical trials. European Neuropsychopharmacology, 24, 737-743.
  • Mason, O., Claridge, G., y Jackson, M. (1995). New scales for the assessment of schizotypy. Personality and Individual Differences, 18, 7-13.
  • McGrath, J., Saha, S., Chant, D., y Welham, J. (2008). Schizophrenia: a concise overview of incidence, prevalence, and mortality. Epidemiologic Reviews, 30, 67-76.
  • Meehl, P. E. (1962). Schizotaxia, schizotypy, schizophrenia. American Psychologist, 17(12), 827-838.
  • Miller, T. J., McGlashan, T. H., Rosen, J. L., Cadenhead, K., Ventura, J., McFarlane, W., . . . Woods, S. W. (2003). Prodromal Assessment with the Structured Interview for Prodromal Syndromes and the Scale of Prodromal Symptoms: Predictive Validity, Interrater Reliability, and Training to Reliability. Schizophrenia Bulletin, 29(4), 703-715.
  • Obiols, J., Barrantes-Vidal, N., y Zaragoza Domingo, S. (2006). La evaluación clínica y psicométrica de los trastornos del espectro esquizofrénico. En V. E. Caballo (Ed.), Manual para la evaluación clínica de los trastornos psicológicos: trastornos de la edad adulta e informes psicológicos (pp. 65-88). Madrid: Ediciones Pirámide.
  • Obiols, J. E., Barragán, M., Vicens, J., y Navarro, J. B. (2008). Síntomas seudo-psicóticos en adolescentes de la población general. Revista de Psicopatología y Psicología Clínica, 13, 205 217.
  • Obiols, J. E., Salvador, J., Humbert, M., y Obiols, J. (1985). Evaluación de los síntomas negativos de la esquizofrenia. Revista del Departamento de Psiquiatría. Facultad de Medicina de Barcelona, 12, 85-91.
  • Olesen, J., Gustavsson, A., Svensson, M., Wittchen, H. U., y Jönsson, B. (2012). The economic cost of brain disorders in Europe. European Journal of Neurology, 19, 155-162.
  • Oorschot, M., Kwapil, T., Delespaul, P., y Myin-Germeys, I. (2009). Momentary assessment research in psychosis. Psychological Assessment, 21, 498-505.
  • Park, S. G., Llerena, K., McCarthy, J. M., Couture, S. M., Bennett, M. E., y Blanchard, J. J. (2012). Screening for negative symptoms: Preliminary results from the self-report version of the Clinical Assessment Interview for Negative Symptoms. Schizophrenia Research, 135(1-3), 139-143.
  • Perälä, J., Suvisaari, J., Saarni, S. I., Kuoppasalmi, K., Isometsä, E., Pirkola, S., . . . Lönnqvist, J. (2007). Lifetime prevalence of psychotic and bipolar I disorders in a general population. Archives of General Psychiatry, 64(1), 19-28.
  • Peralta, V., y Cuesta, M. J. (1994). Psychometric properties of the positive and negative syndrome scale (PANSS) in schizophrenia. Psychiatry Research, 53, 31-40.
  • Pratt, S., y Mueser, K. T. (2010). Schizophrenia. En M. M. Antoni y D. H. Barlow (Eds.), Handbook of assessment and treatment planning for psychological disorders (Second ed., pp. 477-528). New York, NY: Guilford Press.
  • Raine, A. (1991). The SPQ: A scale for the assessment of schizotypal personality based on DSM-III-R criteria. Schizophrenia Bulletin, 17, 555-564.
  • Reininghaus, U., Priebe, S., y Bentall, R. P. (2013). Testing the psychopathology of psychosis: evidence for a general psychosis dimension. Schizophrenia Bulletin, 38, 884-895.
  • Ritsner, M. S. (2013). Anhedonia: A Comprehensive Handbook (Vol. I). New York: Springer.
  • Rodriguez-Jimenez, R., Bagney, A., Mezquita, L., Martinez-Gras, I., Sanchez-Morla, E. M., Mesa, N., . . . PARG. (2013). Cognition and the five-factor model of the positive and negative syndrome scale in schizophrenia. Schizophrenia Research, 143, 77-83.
  • Ros-Morente, A., Rodriguez-Hansen, G., Vilagrá-Ruiz, R., Kwapil, T. R., y Barrantes-Vidal, N. (2010). Adaptation of the wisconsin scales of psychosis proneness to Spanish. Actas Españolas de Psiquiatría, 38, 33-41.
  • Ros-Morente, A., Vilagra-Ruiz, R., Rodriguez-Hansen, G., Wigman, J. H., y Barrantes-Vidal, N. (2011). Process of adaptation to Spanish of the Community Assessment of Psychic Experiences (CAPE). Actas Españolas de Psiquiatría, 39, 95-105.
  • Stefanis, N. C., Hanssen, M., Smirnis, N. K., Avramopoulos, D. A., Evdokimidis, I. K., Stefanis, C. N., . . . Van Os, J. (2002). Evidence that three dimensions of psychosis have a distribution in the general population. Psychological Medicine, 32(2), 347-358.
  • Strauss, G. P., y Gold, J. M. (2012). A New Perspective on Anhedonia in Schizophrenia. American Journal of Psychiatry, 169, 364-373.
  • Tarbox, S. I., y Pogue-Geile, M. F. (2011). A multivariate perspective on schizotypy and familial association with schizophrenia: a review. Clinical Psychology Review, 31, 1169-1182.
  • Valmaggia, L. R., Stahl, D., Yung, A. R., Nelson, B., Fusar-Poli, P., McGorry, P. D., y McGuire, P. K. (2013). Negative psychotic symptoms and impaired role functioning predict transition outcomes in the at-risk mental state: a latent class cluster analysis study. Psychological Medicine, 43, 2311-2325.
  • van Os, J., y Kapur, S. (2009). Schizophrenia. Lancet, 374, 635-645.
  • Velligan, D. I., Alphs, L., Lancaster, S., Morlock, R., y Mintz, J. (2009). Association between changes on the Negative Symptom Assessment scale (NSA-16) and measures of functional outcome in schizophrenia. Psychiatry Research, 169, 97-100.
  • Wolf, D. H., Satterthwaite, T. D., Kantrowitz, J. J., Katchmar, N., Vandekar, L., Elliott, M. A., y Ruparel, K. (2014). Amotivation in schizophrenia: Integrated assessment with behavioral, clinical, and imaging measures. Schizophrenia Bulletin, 40(6),1328-1337.
  • Yung, A. R., Yuen, H. P., McGorry, P. D., Phillips, L. J., Kelly, D., Dell'Olio, M., . . . Buckby, J. (2005). Mapping the onset of psychosis-the Comprehensive Assessment of At Risk Mental States (CAARMS). Australian and New Zealand Journal of Psychiatry, 39, 964- 971.