Química
Departamento
Ramon
Hurtado-Guerrero
Publicaciones en las que colabora con Ramon Hurtado-Guerrero (35)
2024
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A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases
Nature Catalysis
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Correction to: Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase (Nature Communications, (2023), 14, 1, (5785), 10.1038/s41467-023-41238-1)
Nature Communications
2023
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Molecular Recognition of GalNAc in Mucin-Type O-Glycosylation
Accounts of Chemical Research, Vol. 56, Núm. 5, pp. 548-560
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Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase
Nature Communications, Vol. 14, Núm. 1
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Structure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses
JACS Au
2022
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Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
JACS AU, Vol. 2, Núm. 3, pp. 631-645
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Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment
Biomedicines, Vol. 10, Núm. 6
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Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut
Nature Communications, Vol. 13, Núm. 1
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Structural basis for the synthesis of the core 1 structure by C1GalT1
Nature Communications, Vol. 13, Núm. 1
2021
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FUT8-Directed Core Fucosylation of N-glycans Is Regulated by the Glycan Structure and Protein Environment
ACS Catalysis, Vol. 11, Núm. 15, pp. 9052-9065
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Fucosyltransferase-specific inhibitionvianext generation of fucose mimetics
Chemical Communications, Vol. 57, Núm. 9, pp. 1145-1148
2020
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Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3
Nature Chemical Biology, Vol. 16, Núm. 3, pp. 351-360
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Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase
Nature Communications, Vol. 11, Núm. 1
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Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody
Chemical Communications, Vol. 56, Núm. 96, pp. 15137-15140
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Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
Chemical Science, Vol. 11, Núm. 15, pp. 3996-4006
2019
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
2018
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Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions
Molecular Cell, Vol. 71, Núm. 5, pp. 718-732.e9
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Structural Analysis of a GalNAc-T2 Mutant Reveals an Induced-Fit Catalytic Mechanism for GalNAc-Ts
Chemistry - A European Journal, Vol. 24, Núm. 33, pp. 8382-8392
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Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4
ACS Central Science, Vol. 4, Núm. 9, pp. 1274-1290
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The use of fluoroproline in MUC1 antigen enables efficient detection of antibodies inpatients with cancer
29th International Carbohydrate Symposium - ICS2018