Ismael
Compañón Pérez
Investigador en el periodo 2014-2022
Ikerbasque, Fundación Vasca para la Ciencia
Bilbao, EspañaPublicaciones en colaboración con investigadores/as de Ikerbasque, Fundación Vasca para la Ciencia (10)
2022
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Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
JACS AU, Vol. 2, Núm. 3, pp. 631-645
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
2019
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Conformational Behavior of D-Lyxose in Gas and Solution Phases by Rotational and NMR Spectroscopies
Journal of Physical Chemistry Letters, Vol. 10, Núm. 12, pp. 3339-3345
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
2018
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Oxygen by Carbon Replacement at the Glycosidic Linkage Modulates the Sugar Conformation in Tn Antigen Mimics
ACS Omega, Vol. 3, Núm. 12, pp. 18142-18152
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Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4
ACS Central Science, Vol. 4, Núm. 9, pp. 1274-1290
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Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
Journal of the American Chemical Society, Vol. 140, Núm. 31, pp. 9952-9960
2017
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The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18255-18261
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The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences
Nature Communications, Vol. 8, Núm. 1
2016
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Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety
Journal of Organic Chemistry, Vol. 81, Núm. 14, pp. 5929-5941