Publicaciones en colaboración con investigadores/as de Universidade de Lisboa (25)

2023

  1. Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C-C Bond Cleavage Reactions

    Journal of the American Chemical Society, Vol. 145, Núm. 19, pp. 10790-10799

  2. Merging the Isonitrile-Tetrazine (4+1) Cycloaddition and the Ugi Four-Component Reaction into a Single Multicomponent Process

    Angewandte Chemie - International Edition, Vol. 62, Núm. 44

2022

  1. Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination

    Nature Chemistry, Vol. 14, Núm. 7, pp. 754-765

  2. Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

    Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294

2021

  1. Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions

    Bioconjugate Chemistry, Vol. 32, Núm. 8, pp. 1812-1822

2020

  1. Acetals as acid-sensitive clevable linkers for the design of antibody-drug conjugates

    V Chemical Biology Group Meeting (V GEQB)

  2. Precise Installation of Diazo-Tagged Side-Chains on Proteins to Enable in Vitro and In-Cell Site-Specific Labeling

    Bioconjugate Chemistry, Vol. 31, Núm. 6, pp. 1604-1610

  3. Sequential dual site-selective protein labelling enabled by lysine modification

    Bioorganic and Medicinal Chemistry, Vol. 28, Núm. 22

  4. Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation

    Angewandte Chemie - International Edition, Vol. 59, Núm. 15, pp. 6196-6200

2019

  1. Azabicyclic vinyl sulfones for residue-specific dual protein labelling

    Chemical Science, Vol. 10, Núm. 16, pp. 4515-4522

  2. Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents

    Nature Protocols, Vol. 14, Núm. 1, pp. 86-99

  3. Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification

    ACS Central Science, Vol. 5, Núm. 8, pp. 1417-1424

  4. Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent

    Methods in Molecular Biology (Humana Press Inc.), pp. 25-37

  5. Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation

    Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644

  6. Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

    Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072

  7. Tetrazine-Triggered Release of Carboxylic-Acid-Containing Molecules for Activation of an Anti-inflammatory Drug

    ChemBioChem

2018

  1. Chemo- and Regioselective Lysine Modification on Native Proteins

    Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017

  2. Oxidative activation of C-S bonds with an electropositive nitrogen promoter enable orthogonal glycosylation of alkyl ove phenyl thioglycosides

    29th International Carbohydrate Symposium

  3. Radical-Mediated Thiol-Ene Strategy: Photoactivation of Thiol-Containing Drugs in Cancer Cells

    Angewandte Chemie - International Edition, Vol. 57, Núm. 48, pp. 15832-15835

2017

  1. Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation

    Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18365-18375