Gonzalo
Jiménez Osés
Investigador en el periodo 2006-2018
Gonçalo
Bernardes
Publicaciones en las que colabora con Gonçalo Bernardes (18)
2022
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Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
Journal of the American Chemical Society, Vol. 144, Núm. 23, pp. 10396-10406
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
2021
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Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions
Bioconjugate Chemistry, Vol. 32, Núm. 8, pp. 1812-1822
2020
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Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation
Angewandte Chemie - International Edition, Vol. 59, Núm. 15, pp. 6196-6200
2019
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Azabicyclic vinyl sulfones for residue-specific dual protein labelling
Chemical Science, Vol. 10, Núm. 16, pp. 4515-4522
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Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
Nature Protocols, Vol. 14, Núm. 1, pp. 86-99
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Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent
Methods in Molecular Biology (Humana Press Inc.), pp. 25-37
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Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation
Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
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Tetrazine-Triggered Release of Carboxylic-Acid-Containing Molecules for Activation of an Anti-inflammatory Drug
ChemBioChem
2018
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Chemo- and Regioselective Lysine Modification on Native Proteins
Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017
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Radical-Mediated Thiol-Ene Strategy: Photoactivation of Thiol-Containing Drugs in Cancer Cells
Angewandte Chemie - International Edition, Vol. 57, Núm. 48, pp. 15832-15835
2017
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Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation
Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18365-18375
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Oxidative activation of C-S bonds with an electropositive nitrogen promoter enables orthogonal glycosylation of alkyl over phenyl thioglycosides
Organic Letters, Vol. 19, Núm. 19, pp. 5490-5493
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Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
Angewandte Chemie International, Vol. 56, Núm. 1, pp. 243-247
2016
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A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
Angewandte Chemie International, Vol. 55, Núm. 47, pp. 14683-14687
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Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
Nature Communications, Vol. 7
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Tn Antigen Mimics Based on sp2-Iminosugars with Affinity for an anti-MUC1 Antibody
Organic Letters, Vol. 18, Núm. 15, pp. 3890-3893