Gonzalo
Jiménez Osés
Investigador en el periodo 2006-2018
Francisco
Corzana López
CATEDRÁTICO DE UNIVERSIDAD
Publicaciones en las que colabora con Francisco Corzana López (50)
2022
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Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
Journal of the American Chemical Society, Vol. 144, Núm. 23, pp. 10396-10406
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
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Synthesis of β2,2-Amino Acids by Stereoselective Alkylation of Isoserine Derivatives Followed by Nucleophilic Ring Opening of Quaternary Sulfamidates
The Journal of Organic Chemistry, Vol. 87, Núm. 13, pp. 8730-8743
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Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine
Journal of Organic Chemistry, Vol. 87, Núm. 21, pp. 14308-14318
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Towards enantiomerically pure β-seleno-α-amino acids via stereoselective Se-Michael addicions to chiral dehydroalanines
XXXVIII Reunión Bienal de la Real Sociedad Española de Química - RSEQ 2022 (Abstracts book)
2021
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Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions
Bioconjugate Chemistry, Vol. 32, Núm. 8, pp. 1812-1822
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Identification of Isomeric N-Glycans by Conformer Distribution Fingerprinting using Ion Mobility Mass Spectrometry
Chemistry - A European Journal, Vol. 27, Núm. 6, pp. 2149-2154
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Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective Se-Michael Additions to Chiral Dehydroalanines
Organic Letters, Vol. 23, Núm. 6, pp. 1955-1959
2020
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Acetals as acid-sensitive clevable linkers for the design of antibody-drug conjugates
V Chemical Biology Group Meeting (V GEQB)
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Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions
Journal of the American Chemical Society, Vol. 142, Núm. 28, pp. 12501-12514
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Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation
Angewandte Chemie - International Edition, Vol. 59, Núm. 15, pp. 6196-6200
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Synthesis of Nβ-Substituted α,β-Diamino Acids via Stereoselective N-Michael Additions to a Chiral Bicyclic Dehydroalanine
Journal of Organic Chemistry, Vol. 85, Núm. 5, pp. 3134-3145
2019
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Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
Nature Protocols, Vol. 14, Núm. 1, pp. 86-99
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Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification
ACS Central Science, Vol. 5, Núm. 8, pp. 1417-1424
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Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/πand Cation/πInteractions for the Stabilization of Glycosyl-Oxocarbenium Ions
Journal of the American Chemical Society, Vol. 141, Núm. 34, pp. 13372-13384
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Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation
Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
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Síntesis y reactividad de N,O‐acetales bicíclicos derivados de isoserina
X Jornada de Química CISQ
2018
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Cell-Penetrating Peptides Containing Fluorescent d-Cysteines
Chemistry - A European Journal, Vol. 24, Núm. 31, pp. 7991-8000
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Chemo- and Regioselective Lysine Modification on Native Proteins
Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017