Publicaciones en colaboración con investigadores/as de Universidad de Zaragoza (41)

2024

  1. A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases

    Nature Catalysis, Vol. 7, Núm. 4, pp. 386-400

  2. Correction to: Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase (Nature Communications, (2023), 14, 1, (5785), 10.1038/s41467-023-41238-1)

    Nature Communications

  3. Detection of Tumor-Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes

    Angewandte Chemie - International Edition, Vol. 63, Núm. 37

  4. Identification of Tumor-Linked Pancreatic Cancer Autoantibodies in Patients’ sera Through Engineered Glycopeptides

    XXIX RSEQ Biennial Meeting in Organic Chemistry: Santa Cruz de Tenerife, June 26-28, 2024: Abstract Book

  5. Rational Design of Dual-Domain Binding Inhibitors for N-Acetylgalactosamine Transferase 2 with Improved Selectivity over the T1 and T3 Isoforms

    JACS Au, Vol. 4, Núm. 9, pp. 3649-3656

2023

  1. Methyl-to-Ethyl Replacement Makes the Difference: Structure-Guided Design of a New Cancer Vaccine Based on a Tn An-gen Surrogate

    VI RSEQ Chemical Biology Group Meeting - ChemBio VI

  2. Molecular Recognition of GalNAc in Mucin-Type O-Glycosylation

    Accounts of Chemical Research, Vol. 56, Núm. 5, pp. 548-560

  3. Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase

    Nature Communications, Vol. 14, Núm. 1

2022

  1. Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling

    JACS AU, Vol. 2, Núm. 3, pp. 631-645

  2. Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment

    Biomedicines, Vol. 10, Núm. 6

  3. Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut

    Nature Communications, Vol. 13, Núm. 1

  4. Structural basis for the synthesis of the core 1 structure by C1GalT1

    Nature Communications, Vol. 13, Núm. 1

2021

  1. FUT8-Directed Core Fucosylation of N-glycans Is Regulated by the Glycan Structure and Protein Environment

    ACS Catalysis, Vol. 11, Núm. 15, pp. 9052-9065

  2. Fucosyltransferase-specific inhibitionvianext generation of fucose mimetics

    Chemical Communications, Vol. 57, Núm. 9, pp. 1145-1148

2020

  1. Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions

    Journal of the American Chemical Society, Vol. 142, Núm. 28, pp. 12501-12514

  2. Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3

    Nature Chemical Biology, Vol. 16, Núm. 3, pp. 351-360

  3. Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase

    Nature Communications, Vol. 11, Núm. 1

  4. Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody

    Chemical Communications, Vol. 56, Núm. 96, pp. 15137-15140

  5. Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment

    Chemical Science, Vol. 11, Núm. 15, pp. 3996-4006

2019

  1. Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

    Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072