Publicaciones en colaboración con investigadores/as de Instituto de Química Física Rocasolano (13)

2022

  1. Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets

    Communications Chemistry, Vol. 5, Núm. 1

2021

  1. De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot

    Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 27, Núm. 20, pp. 6204-6212

  2. De Novo Design of Selective Quadruplex–Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot

    Chemistry - A European Journal

2016

  1. Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders

    Journal of the American Chemical Society, Vol. 138, Núm. 20, pp. 6463-6474

2013

  1. A dynamic combinatorial approach for the analysis of weak carbohydrate/aromatic complexes: Dissecting facial selectivity in CH/π stacking interactions

    Journal of the American Chemical Society, Vol. 135, Núm. 9, pp. 3347-3350

  2. Chemical interrogation of drug/RNA complexes: From chemical reactivity to drug design

    Angewandte Chemie International, Vol. 52, Núm. 11, pp. 3148-3151

2010

  1. Role of Aromatic Rings in the Molecular Recognition of Aminoglycoside Antibiotics: Implications for Drug Design

    Journal of the American Chemical Society, Vol. 132, Núm. 34, pp. 12074-12090

  2. Structural-based Design of Highly Crowded Ribostamycin/Kanamycin Hybrids as a new Family of Antibiotics

    Chemistry - A European Journal, Vol. 16, Núm. 10, pp. 2986-2991

2009

  1. Role of conserved Salt bridges in homeodomain stability and DNA binding

    Journal of Biological Chemistry (Print), Vol. 284, Núm. 35, pp. 23765-23779

2008

  1. NMR-Based Analysis of Aminoglycoside Recognition by the Resistance Enzyme ANT(4′): The Pattern of OH/NH3+ Substitution Determines the Preferred Antibiotic Binding Mode and is Critical for Drug Inactivation

    Journal of the American Chemical Society, Vol. 130, Núm. 15, pp. 5086-5103

2007

  1. A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition. Dramatic alterations in neomycin-B protonation state upon binding to a 23-mer RNA aptamer

    Chemical Communications, Vol. 2, Núm. 2, pp. 174-176

2006

  1. Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance

    Journal of the American Chemical Society, Vol. 128, Núm. 1, pp. 100-116

2005

  1. Molecular recognition of aminoglycoside antibiotics by bacterial defense proteins: NMR study of the structural and conformational features of streptomycin inactivation by bacillus subtilis Aminoglycoside-6-adenyl Transferase

    Chemistry - A European Journal, Vol. 11, Núm. 17, pp. 5102-5113