Xhenti
Ferhati
Investigadora en el periodo 2016-2019
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University of Cambridge
Cambridge, Reino UnidoPublicaciones en colaboración con investigadores/as de University of Cambridge (8)
2022
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New bioorthogonal self-immolative linker based on the Grob fragmentation reaction
XXVIII Reunión Bienal GEQOR (Grupo Especializado de Química Orgánica). Libro de abstracts
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
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Synthesis and study of a new bioorthogonal self-immolative linker based on the Grob fragmentation reaction
XXXVIII Reunión Bienal de la Real Sociedad Española de Química - RSEQ 2022 (Abstracts book)
2021
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Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation
Organic Letters, Vol. 23, Núm. 21, pp. 8580-8584
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Effect of Lys-207 of trastuzumab on stability of antibody-drug conjugates bearing linkers based on acetals and thiol-maleimide chemistry
XI Jornada de Química CISQ
2020
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Acetals as acid-sensitive clevable linkers for the design of antibody-drug conjugates
V Chemical Biology Group Meeting (V GEQB)
2019
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Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
Nature Protocols, Vol. 14, Núm. 1, pp. 86-99
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Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation
Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644