Publicacións en colaboración con investigadores/as de University of Cambridge (41)

2024

  1. Non-natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity

    XXIX RSEQ Biennial Meeting in Organic Chemistry: Santa Cruz de Tenerife, June 26-28, 2024: Abstract Book

  2. Non‐natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity

    Angewandte Chemie International Edition

2023

  1. Methyl-to-Ethyl Replacement Makes the Difference: Structure-Guided Design of a New Cancer Vaccine Based on a Tn An-gen Surrogate

    VI RSEQ Chemical Biology Group Meeting - ChemBio VI

  2. Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules

    ACS Central Science, Vol. 9, Núm. 5, pp. 892-904

2022

  1. New bioorthogonal self-immolative linker based on the Grob fragmentation reaction

    XXVIII Reunión Bienal GEQOR (Grupo Especializado de Química Orgánica). Libro de abstracts

  2. Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents

    Journal of the American Chemical Society, Vol. 144, Núm. 23, pp. 10396-10406

  3. Selective Inhibition of Bruton’s Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors

    ACS Pharmacology and Translational Science, Vol. 5, Núm. 11, pp. 1156-1168

  4. Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

    Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294

  5. Synthesis and study of a new bioorthogonal self-immolative linker based on the Grob fragmentation reaction

    XXXVIII Reunión Bienal de la Real Sociedad Española de Química - RSEQ 2022 (Abstracts book)

2021

  1. Accelerating Reaction Rates of Biomolecules by Using Shear Stress in Artificial Capillary Systems

    Journal of the American Chemical Society, Vol. 143, Núm. 40, pp. 16401-16410

  2. Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression

    ACS Central Science, Vol. 7, Núm. 5, pp. 868-881

  3. Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions

    Bioconjugate Chemistry, Vol. 32, Núm. 8, pp. 1812-1822

  4. Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation

    Organic Letters, Vol. 23, Núm. 21, pp. 8580-8584

  5. Dichloro Butenediamides as Irreversible Site-Selective Protein Conjugation Reagent

    Angewandte Chemie - International Edition, Vol. 60, Núm. 44, pp. 23750-23755

  6. Effect of Lys-207 of trastuzumab on stability of antibody-drug conjugates bearing linkers based on acetals and thiol-maleimide chemistry

    XI Jornada de Química CISQ

2020

  1. Acetals as acid-sensitive clevable linkers for the design of antibody-drug conjugates

    V Chemical Biology Group Meeting (V GEQB)

  2. Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects

    Cell Metabolism, Vol. 31, Núm. 6, pp. 1120-1135.e7

  3. Precise protein conjugation technology for the construction of homogenous glycovaccines

    Drug Discovery Today: Technologies, Vol. 38, pp. 69-75

  4. Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation

    Angewandte Chemie - International Edition, Vol. 59, Núm. 15, pp. 6196-6200

  5. Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

    RSC Chemical Biology, Vol. 1, Núm. 4, pp. 251-262