Diseño y estructura de glicopéptidos con relevancia biológica
Glycopep4life
Universidad del País Vasco/Euskal Herriko Unibertsitatea
Lejona, EspañaPublicacións en colaboración con investigadores/as de Universidad del País Vasco/Euskal Herriko Unibertsitatea (20)
2023
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Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
Nature Communications, Vol. 14, Núm. 1
2022
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Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
JACS AU, Vol. 2, Núm. 3, pp. 631-645
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Fluorination and deoxygenation as chemical tools to study the conformational preferences of hexopyranoses: a journey from gas phase to solution
75th International Symposium on Molecular Spectroscopy
2021
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Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium
Journal of Physical Chemistry Letters, Vol. 12, Núm. 4, pp. 1352-1359
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Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA
Science Advances, Vol. 7, Núm. 42
2020
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Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria
Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945
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Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars
ACS Central Science, Vol. 6, Núm. 2, pp. 293-303
2019
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Conformational Behavior of D-Lyxose in Gas and Solution Phases by Rotational and NMR Spectroscopies
Journal of Physical Chemistry Letters, Vol. 10, Núm. 12, pp. 3339-3345
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
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The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose-Type Lectin
Chemistry - A European Journal, Vol. 25, Núm. 61, pp. 13945-13955
2018
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Structural Analysis of a GalNAc-T2 Mutant Reveals an Induced-Fit Catalytic Mechanism for GalNAc-Ts
Chemistry - A European Journal, Vol. 24, Núm. 33, pp. 8382-8392
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Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4
ACS Central Science, Vol. 4, Núm. 9, pp. 1274-1290
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The Conformation of the Mannopyranosyl Phosphate Repeating Unit of the Capsular Polysaccharide of Neisseria meningitidis Serogroup A and Its Carba-Mimetic
European Journal of Organic Chemistry, Vol. 2018, Núm. 33, pp. 4548-4555
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Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
Journal of the American Chemical Society, Vol. 140, Núm. 31, pp. 9952-9960
2017
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Conformational study of DNA sugars: from the gas phase to solution
72nd International Symposium on Molecular Spectroscopy
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The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18255-18261
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The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences
Nature Communications, Vol. 8, Núm. 1
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Untangling Tn antigen structure and its first hydration shell
28th Joint Glycobiology Meeting 2017
2016
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Diastereomeric Glycosyl Sulfoxides Display Different Recognition Features versus E. coli β-Galactosidase
European Journal of Organic Chemistry, Vol. 2016, Núm. 30, pp. 5117-5122
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Unraveling the Conformational Landscape of Ligand Binding to Glucose/Galactose-Binding Protein by Paramagnetic NMR and MD Simulations
ACS chemical biology, Vol. 11, Núm. 8, pp. 2149-2157