Diseño y estructura de glicopéptidos con relevancia biológica
Glycopep4life
Centro de Investigación Cooperativa en Biotecnología
Zamudio, EspañaPublicacions en col·laboració amb investigadors/es de Centro de Investigación Cooperativa en Biotecnología (40)
2024
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Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/π Complexes with Dynamic Covalent Glyco-Balances
XXIX RSEQ Biennial Meeting in Organic Chemistry: Santa Cruz de Tenerife, June 26-28, 2024: Abstract Book
2023
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Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Nature communications, Vol. 14, Núm. 1, pp. 1705
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Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
Nature Communications, Vol. 14, Núm. 1
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Turning universal O into rare Bombay type blood
Nature communications, Vol. 14, Núm. 1, pp. 1765
2022
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Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
JACS AU, Vol. 2, Núm. 3, pp. 631-645
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Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets
Communications Chemistry, Vol. 5, Núm. 1
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Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
Journal of the American Chemical Society, Vol. 144, Núm. 23, pp. 10396-10406
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
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Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine
Journal of Organic Chemistry, Vol. 87, Núm. 21, pp. 14308-14318
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Towards enantiomerically pure β-seleno-α-amino acids via stereoselective Se-Michael addicions to chiral dehydroalanines
XXXVIII Reunión Bienal de la Real Sociedad Española de Química - RSEQ 2022 (Abstracts book)
2021
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Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions
Bioconjugate Chemistry, Vol. 32, Núm. 8, pp. 1812-1822
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Effect of Lys-207 of trastuzumab on stability of antibody-drug conjugates bearing linkers based on acetals and thiol-maleimide chemistry
XI Jornada de Química CISQ
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Identification of Isomeric N-Glycans by Conformer Distribution Fingerprinting using Ion Mobility Mass Spectrometry
Chemistry - A European Journal, Vol. 27, Núm. 6, pp. 2149-2154
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Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA
Science Advances, Vol. 7, Núm. 42
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Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins
Chemistry - A European Journal, Vol. 27, Núm. 29, pp. 7951-7958
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Síntesis de β-seleno-α-aminoácidos enantioméricamente puros mediante adiciones Se-Michael estereoselectivas a deshidroalaninas quirales
XI Jornada de Química CISQ
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Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective Se-Michael Additions to Chiral Dehydroalanines
Organic Letters, Vol. 23, Núm. 6, pp. 1955-1959
2020
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Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions
Journal of the American Chemical Society, Vol. 142, Núm. 28, pp. 12501-12514
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Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria
Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945
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Exploiting structure-activity relationships of QS-21 in the design and synthesis of streamlined saponin vaccine adjuvants
Chemical Communications, Vol. 56, Núm. 5, pp. 719-722