Diseño y estructura de glicopéptidos con relevancia biológica
Glycopep4life
Ikerbasque, Fundación Vasca para la Ciencia
Bilbao, EspañaPublicacions en col·laboració amb investigadors/es de Ikerbasque, Fundación Vasca para la Ciencia (24)
2024
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Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/Π Complexes with Dynamic Covalent Glyco-Balances
7th Iberian Carbohydrate Meeting: Abstract book
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Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/π Complexes with Dynamic Covalent Glyco-Balances
JACS Au, Vol. 4, Núm. 2, pp. 476-490
2023
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Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
Nature Communications, Vol. 14, Núm. 1
2022
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Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
JACS AU, Vol. 2, Núm. 3, pp. 631-645
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Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
Journal of the American Chemical Society, Vol. 144, Núm. 23, pp. 10396-10406
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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry
Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294
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Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine
Journal of Organic Chemistry, Vol. 87, Núm. 21, pp. 14308-14318
2021
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Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions
Bioconjugate Chemistry, Vol. 32, Núm. 8, pp. 1812-1822
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Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA
Science Advances, Vol. 7, Núm. 42
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Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins
Chemistry - A European Journal, Vol. 27, Núm. 29, pp. 7951-7958
2020
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Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions
Journal of the American Chemical Society, Vol. 142, Núm. 28, pp. 12501-12514
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Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria
Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945
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Exploiting structure-activity relationships of QS-21 in the design and synthesis of streamlined saponin vaccine adjuvants
Chemical Communications, Vol. 56, Núm. 5, pp. 719-722
2019
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Conformational Behavior of D-Lyxose in Gas and Solution Phases by Rotational and NMR Spectroscopies
Journal of Physical Chemistry Letters, Vol. 10, Núm. 12, pp. 3339-3345
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Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/πand Cation/πInteractions for the Stabilization of Glycosyl-Oxocarbenium Ions
Journal of the American Chemical Society, Vol. 141, Núm. 34, pp. 13372-13384
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
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The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose-Type Lectin
Chemistry - A European Journal, Vol. 25, Núm. 61, pp. 13945-13955
2018
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Oxygen by Carbon Replacement at the Glycosidic Linkage Modulates the Sugar Conformation in Tn Antigen Mimics
ACS Omega, Vol. 3, Núm. 12, pp. 18142-18152
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Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4
ACS Central Science, Vol. 4, Núm. 9, pp. 1274-1290
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The Conformation of the Mannopyranosyl Phosphate Repeating Unit of the Capsular Polysaccharide of Neisseria meningitidis Serogroup A and Its Carba-Mimetic
European Journal of Organic Chemistry, Vol. 2018, Núm. 33, pp. 4548-4555