Publications by the researcher in collaboration with Ramon Hurtado-Guerrero (34)

2024

  1. A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases

    Nature Catalysis

  2. Correction to: Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase (Nature Communications, (2023), 14, 1, (5785), 10.1038/s41467-023-41238-1)

    Nature Communications

2023

  1. Molecular Recognition of GalNAc in Mucin-Type O-Glycosylation

    Accounts of Chemical Research, Vol. 56, Núm. 5, pp. 548-560

  2. Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase

    Nature Communications, Vol. 14, Núm. 1

  3. Structure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses

    JACS Au

2022

  1. Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling

    JACS AU, Vol. 2, Núm. 3, pp. 631-645

  2. Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment

    Biomedicines, Vol. 10, Núm. 6

  3. Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut

    Nature Communications, Vol. 13, Núm. 1

  4. Structural basis for the synthesis of the core 1 structure by C1GalT1

    Nature Communications, Vol. 13, Núm. 1

2021

  1. FUT8-Directed Core Fucosylation of N-glycans Is Regulated by the Glycan Structure and Protein Environment

    ACS Catalysis, Vol. 11, Núm. 15, pp. 9052-9065

  2. Fucosyltransferase-specific inhibitionvianext generation of fucose mimetics

    Chemical Communications, Vol. 57, Núm. 9, pp. 1145-1148

2020

  1. Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3

    Nature Chemical Biology, Vol. 16, Núm. 3, pp. 351-360

  2. Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase

    Nature Communications, Vol. 11, Núm. 1

  3. Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody

    Chemical Communications, Vol. 56, Núm. 96, pp. 15137-15140

  4. Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment

    Chemical Science, Vol. 11, Núm. 15, pp. 3996-4006

2019

  1. Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

    Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072

2018

  1. Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions

    Molecular Cell, Vol. 71, Núm. 5, pp. 718-732.e9

  2. Structural Analysis of a GalNAc-T2 Mutant Reveals an Induced-Fit Catalytic Mechanism for GalNAc-Ts

    Chemistry - A European Journal, Vol. 24, Núm. 33, pp. 8382-8392

  3. Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4

    ACS Central Science, Vol. 4, Núm. 9, pp. 1274-1290

  4. Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition

    Journal of the American Chemical Society, Vol. 140, Núm. 31, pp. 9952-9960