Juan Luis
Asensio Alvarez
Publicaciones en las que colabora con Juan Luis Asensio Alvarez (43)
2024
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Detection of Tumor-Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes
Angewandte Chemie - International Edition, Vol. 63, Núm. 37
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Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/Π Complexes with Dynamic Covalent Glyco-Balances
7th Iberian Carbohydrate Meeting: Abstract book
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Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/π Complexes with Dynamic Covalent Glyco-Balances
JACS Au, Vol. 4, Núm. 2, pp. 476-490
2022
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Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets
Communications Chemistry, Vol. 5, Núm. 1
2021
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De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot
Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 27, Núm. 20, pp. 6204-6212
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De Novo Design of Selective Quadruplex–Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot
Chemistry - A European Journal
2020
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Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions
Journal of the American Chemical Society, Vol. 142, Núm. 28, pp. 12501-12514
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Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody
Chemical Communications, Vol. 56, Núm. 96, pp. 15137-15140
2019
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Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/πand Cation/πInteractions for the Stabilization of Glycosyl-Oxocarbenium Ions
Journal of the American Chemical Society, Vol. 141, Núm. 34, pp. 13372-13384
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
2018
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Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
Journal of the American Chemical Society, Vol. 140, Núm. 31, pp. 9952-9960
2017
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A dynamic combinatorial chemistry approach to quantify the contribution of electrostatics to the stability of CH/Π bonds in water
19th European Carbohydrate Symposium
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The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18255-18261
2016
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Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders
Journal of the American Chemical Society, Vol. 138, Núm. 20, pp. 6463-6474
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Mucin Architecture behind the Immune Response: Design and Evaluation of an Antitumor Vaccine Derived from an Unnatural MUC1 Fragment
Chemical Science, Vol. 7, Núm. 3, pp. 2294
2015
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A thorough experimental study of CH/π interactions in water: quantitative structure-stability relationships for carbohydrate/aromatic complexes
Chemical Science, Vol. 6, Núm. 11, pp. 6076-6085
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Deciphering the Non-Equivalence of Serine and Threonine O-glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
Angewandte Chemie International, Vol. 54, Núm. 34, pp. 9830
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Detection of tumor-associated glycopeptides by Lectins: The peptide context modulates carbohydrate recognition
ACS chemical biology, Vol. 10, Núm. 3, pp. 747-756
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Modulating weak interactions for molecular recognition: A dynamic combinatorial analysis for assessing the contribution of electrostatics to the stability of CH-π bonds in water
Angewandte Chemie International, Vol. 54, Núm. 14, pp. 4344-4348
2014
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Chemical interrogation of drug/RNA complexes: from chemical reactivity to drug design
XI Carbohydrate Symposium