Química Biológica
QuiBi
University of Cambridge
Cambridge, Reino UnidoUniversity of Cambridge-ko ikertzaileekin lankidetzan egindako argitalpenak (13)
2024
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Non-natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity
XXIX RSEQ Biennial Meeting in Organic Chemistry: Santa Cruz de Tenerife, June 26-28, 2024: Abstract Book
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Non‐natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity
Angewandte Chemie International Edition
2023
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Methyl-to-Ethyl Replacement Makes the Difference: Structure-Guided Design of a New Cancer Vaccine Based on a Tn An-gen Surrogate
VI RSEQ Chemical Biology Group Meeting - ChemBio VI
2022
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New bioorthogonal self-immolative linker based on the Grob fragmentation reaction
XXVIII Reunión Bienal GEQOR (Grupo Especializado de Química Orgánica). Libro de abstracts
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Synthesis and study of a new bioorthogonal self-immolative linker based on the Grob fragmentation reaction
XXXVIII Reunión Bienal de la Real Sociedad Española de Química - RSEQ 2022 (Abstracts book)
2021
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Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation
Organic Letters, Vol. 23, Núm. 21, pp. 8580-8584
2020
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Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
Chemical Science, Vol. 11, Núm. 15, pp. 3996-4006
2019
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Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Journal of the American Chemical Society, Vol. 141, Núm. 9, pp. 4063-4072
2018
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The use of fluoroproline in MUC1 antigen enables efficient detection of antibodies inpatients with cancer
29th International Carbohydrate Symposium - ICS2018
2017
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The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18255-18261
2016
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Tn Antigen Mimics Based on sp2-Iminosugars with Affinity for an anti-MUC1 Antibody
Organic Letters, Vol. 18, Núm. 15, pp. 3890-3893
2015
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Deciphering the Non-Equivalence of Serine and Threonine O-glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
Angewandte Chemie International, Vol. 54, Núm. 34, pp. 9830
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Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation
Nature Communications, Vol. 6, pp. 1-12