Structures and properties of Gold(I) Complexes of Interest in Biomedical Applications

  1. Abdou, H.E. 2
  2. Mohamed, A.A. 2
  3. Fackler Jr. 2
  4. Burini, A. 3
  5. Galassi, R. 3
  6. López-de-Luzuriaga, J.M. 1
  7. Olmos, M.E. 1
  1. 1 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

  2. 2 Texas A&M University
    info

    Texas A&M University

    College Station, Estados Unidos

    ROR https://ror.org/01f5ytq51

  3. 3 Università di Camerino
    info

    Università di Camerino

    Camerino, Italia

    ROR https://ror.org/0005w8d69

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Revista:
Coordination Chemistry Reviews

ISSN: 0010-8545

Año de publicación: 2009

Volumen: 253

Número: 11/12/2010

Páginas: 1661-1669

Tipo: Artículo

DOI: 10.1016/J.CCR.2009.02.010 SCOPUS: 2-s2.0-64049110809 WoS: WOS:000266188500007 GOOGLE SCHOLAR

Otras publicaciones en: Coordination Chemistry Reviews

Resumen

Gold(I) compounds have several potential roles in biologically related chemistry. The relatively low toxicity of gold and its lability allows human consumption of drugs formed with this element. Trinuclear and tetranuclear clusters look particularly interesting because of the strong basicity of the gold(I) centers in these molecules. Future studies are expected to lead to interesting new bio-related observations. The ability of gold(I) compounds to interact with themselves aurophilically and with other heavy element ions has produced spectroscopic properties which are sensitive to volatile organic compounds (VOCs) and other molecular interactions. Thus bio-applicability for sensing toxic components appears reasonable. © 2009 Elsevier B.V. All rights reserved.