Early in short days 1 (ESD1) encodes Actin-Related Protein 6 (AtARP6), a putative component of chromatin remodelling complexes that positively regulates FLC accumulation in Arabidopsis

  1. Martin-Trillo, M. 2
  2. Lázaro, A. 1
  3. Scott Poethig, R. 4
  4. Gómez-Mena, C. 23
  5. Piñeiro, M.A. 1
  6. Martinez-Zapater, J.M. 2
  7. Jarillo, J.A. 1
  1. 1 Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
    info

    Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria

    Madrid, España

    ROR https://ror.org/011q66e29

  2. 2 Centro Nacional de Biotecnología
    info

    Centro Nacional de Biotecnología

    Madrid, España

    ROR https://ror.org/015w4v032

  3. 3 John Innes Centre
    info

    John Innes Centre

    Norwich, Reino Unido

    ROR https://ror.org/055zmrh94

  4. 4 University of Pennsylvania
    info

    University of Pennsylvania

    Filadelfia, Estados Unidos

    ROR https://ror.org/00b30xv10

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Revista:
Development

ISSN: 0950-1991

Año de publicación: 2006

Volumen: 133

Número: 7

Páginas: 1241-1252

Tipo: Artículo

DOI: 10.1242/DEV.02301 PMID: 16495307 SCOPUS: 2-s2.0-33646130847 GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Development

Repositorio institucional: lock_openAcceso abierto Editor

Resumen

We have characterized Arabidopsis esd1 mutations, which cause early flowering independently of photoperiod, moderate increase of hypocotyl length, shortened inflorescence internodes, and altered leaf and flower development. Phenotypic analyses of double mutants with mutations at different loci of the flowering inductive pathways suggest that esd1 abolishes the FLC-mediated late flowering phenotype of plants carrying active alleles of FRI and of mutants of the autonomous pathway. We found that ESD1 is required for the expression of the FLC repressor to levels that inhibit flowering. However, the effect of esd1 in a flc-3 null genetic background and the downregulation of other members of the FLC-like/MAF gene family in esd1 mutants suggest that flowering inhibition mediated by ESD1 occurs through both FLC- and FLC-like gene-dependent pathways. The ESD1 locus was identified through a map-based cloning approach. ESD1 encodes ARP6, a homolog of the actin-related protein family that shares moderate sequence homology with conventional actins. Using chromatin immunoprecipitation (ChlP) experiments, we have determined that ARP6 is required for both histone acetylation and methylation of the FLC chromatin in Arabidopsis.