Trimethyltin chloride determination by hydride generation-gas phase molecular absorption spectrometry. A sequential application of experimental designs

  1. Sanz-Asensio, J. 1
  2. Martínez-Soria, M.T. 1
  3. Plaza-Medina, M. 1
  4. Pérez-Clavijo, M. 1
  1. 1 Dept. of Chem. (Analyt. Chemistry), Univ. of la Rioja, Logrono 26001, La Rioja, Spain
Revista:
Analytica Chimica Acta

ISSN: 0003-2670

Año de publicación: 2000

Volumen: 409

Número: 1-2

Páginas: 171-180

Tipo: Artículo

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DOI: 10.1016/S0003-2670(99)00847-8 SCOPUS: 2-s2.0-0342948886 WoS: WOS:000085995900022 GOOGLE SCHOLAR

Otras publicaciones en: Analytica Chimica Acta

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Resumen

In this paper, a sequential experimental design is applied to optimize the determination of trimethyltin chloride (TMT) by hydride generation-gas phase molecular absorption spectrometry. The TMT is converted into gaseous trimethyltin hydride by adding a sodium tetrahydroborate (III) solution. The hydride generated is collected in a liquid nitrogen cryogenic trap. This is revolatilized, driven to the quartz flow cell and measured with gas phase molecular absorption spectrometry with diode array detection. A Plackett-Burman design is used to study the parameters affecting the production, collection and measurement of the hydrides. The optimization of these parameters is achieved using a central composite design. PLS, MLR and univariate calibration are applied to the spectra obtained. The detection and quantification limits are 1.5 and 4.6ngml-1, respectively, and the relative standard deviation (n=10) at 15ngml-1 was 5.5%. An interference study is presented. Copyright (C) 2000 Elsevier Science B.V.