Experimental design methodologies to optimize monobutyltin chloride determination by hydride generation gas phase molecular absorption spectrometry

  1. Sanz, J. 1
  2. Pérez, M. 1
  3. Martínez, M.T. 1
  4. Plaza, M. 1
  1. 1 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

Revista:
Talanta (Oxford)

ISSN: 0039-9140

Año de publicación: 1999

Volumen: 50

Número: 1

Páginas: 149-164

Tipo: Artículo

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DOI: 10.1016/S0039-9140(99)00117-4 SCOPUS: 2-s2.0-0344172742 WoS: WOS:000082773700017 GOOGLE SCHOLAR

Otras publicaciones en: Talanta (Oxford)

Repositorio institucional: lock_openAcceso abierto Editor

Resumen

A hydride generation gas phase molecular absorption spectrometry (HG- GPMAS) method for the determination of butyltin compound is optimized by experimental design. This method is based on the conversion of the butyltin chloride into gaseous monobutyltin hydride by adding a sodium tetrahydroborate (III solution. The hydride generated is collected in a liquid nitrogen cryogenic trap. This is revolatilized, driven to the quartz flow cell and measured with GPMAS with diode array detection. A Plackett- Burmann design is used for the study of the factors that influence the absorption signal. The optimization of the parameters affecting the production and collection of the monobutyltin hydride is achieved using a central composite design. Partial least square (PLS), multiple linear regression (MLR) and univariate calibration are applied to the spectra obtained. The quality parameters (detection limits and precision) for the butyltin chloride are reported. An interference study is made.