Optical Control of Antimicrobial Activity in Quinolone Derivatives

  1. Contreras-García, E. 1
  2. Martínez-López, D. 1
  3. Alonso, C.A. 1
  4. Lozano, C. 12
  5. Torres, C. 12
  6. Rodríguez, M.A. 1
  7. Campos, P.J. 1
  8. Sampedro, D. 1
  1. 1 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

  2. 2 Centro de Investigación Biomédica de La Rioja
    info

    Centro de Investigación Biomédica de La Rioja

    Logroño, España

    ROR https://ror.org/03vfjzd38

Journal:
European Journal of Organic Chemistry

ISSN: 1434-193X

Year of publication: 2017

Volume: 2017

Issue: 32

Pages: 4719-4725

Type: Article

DOI: 10.1002/EJOC.201700809 SCOPUS: 2-s2.0-85028598539 WoS: WOS:000408853700008 GOOGLE SCHOLAR

More publications in: European Journal of Organic Chemistry

Institutional repository: lock_openOpen access postprint
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Metrics

Cited by

  • Scopus Cited by: 7 (06-06-2023)
  • Web of Science Cited by: 6 (20-05-2023)
  • Dimensions Cited by: 6 (30-03-2023)

JCR (Journal Impact Factor)

  • Year 2017
  • Journal Impact Factor: 2.882
  • Journal Impact Factor without self cites: 2.656
  • Article influence score: 0.6
  • Best Quartile: Q2
  • Area: CHEMISTRY, ORGANIC Quartile: Q2 Rank in area: 18/57 (Ranking edition: SCIE)

SCImago Journal Rank

  • Year 2017
  • SJR Journal Impact: 1.037
  • Best Quartile: Q1
  • Area: Physical and Theoretical Chemistry Quartile: Q1 Rank in area: 40/174
  • Area: Organic Chemistry Quartile: Q1 Rank in area: 42/196

Scopus CiteScore

  • Year 2017
  • CiteScore of the Journal : 5.2
  • Area: Organic Chemistry Percentile: 76
  • Area: Physical and Theoretical Chemistry Percentile: 72

Journal Citation Indicator (JCI)

  • Year 2017
  • Journal Citation Indicator (JCI): 0.88
  • Best Quartile: Q2
  • Area: CHEMISTRY, ORGANIC Quartile: Q2 Rank in area: 17/62

Dimensions

(Data updated as of 30-03-2023)
  • Total citations: 6
  • Recent citations: 4
  • Field Citation Ratio (FCR): 0.62

Related Projects

Sistemas fotoactivos: aplicaciones biológicas y de almacenamiento de energía. Photoactive systems: biological applications and energy storage.

2015/00065/001

Abstract

A series of photoswitchable compounds based on the antibiotics nalidixic acid and ciprofloxacin has been designed and prepared. Different photoactive moieties have been used as templates in order to allow for the photocontrol of the antimicrobial properties while providing the adequate photophysical features and solubility required for practical applications. The designed compounds feature strong absorptions up to the visible region, are water-soluble and photoisomerize with high quantum yield. In the best case, a clear difference in the antimicrobial activity expressed as the minimal inhibitory concentration between the initial and the irradiated species was found. The complementary computational study allowed for the rationalization of the results found. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Research Data