VanA mediated vancomycin resistance in Enterococcus isolated in sewage.

  1. Torres, C. 1
  2. Reguera, J.A. 2
  3. Sanmartin, M.J. 1
  4. Pérez-díaz, M.C. 2
  5. Baquero, F. 2
  1. 1 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

  2. 2 Hospital Ramón y Cajal
    info

    Hospital Ramón y Cajal

    Madrid, España

    ROR https://ror.org/050eq1942

Revue:
Journal of Antimicrobial Chemotherapy

ISSN: 0305-7453

Année de publication: 1994

Volumen: 33

Número: 3

Pages: 553-561

Type: Article

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PMID: 8040119 SCOPUS: 2-s2.0-0028204892 WoS: WOS:A1994ND65500016 GOOGLE SCHOLAR

D'autres publications dans: Journal of Antimicrobial Chemotherapy

Résumé

Three high-level vancomycin-resistant Enterococcus strains (two Enterococcus faecium and one Enterococcus durans) were recovered from three of eight sewage samples taken from the general sewage collector at Logrono (Northern Spain). The strains were present in the sewage samples at estimated concentrations of ten resistant bacteria/mL, corresponding to about 0.4% of the enterococcal population. The VanA protein was detected in each strain by immunoblotting of membrane extracts of the vancomycin-induced cells, and the vanA gene was demonstrated in the wild strains and their transconjugants by DNA-DNA hybridization. This is the first, confirmed report of vanA mediated vancomycin resistance in E. durans.