Complex Evolutionary Dynamics of Massively Expanded Chemosensory Receptor Families in an Extreme Generalist Chelicerate Herbivore

  1. Ngoc, P.C. 46
  2. Greenhalgh, R. 2
  3. Dermauw, W. 4
  4. Rombauts, S. 46
  5. Bajda, S. 47
  6. Zhurov, V. 3
  7. Grbić, M. 38
  8. Van de Peer, Y. 1456
  9. Van Leeuwen, T. 47
  10. Rouzé, P. 6
  11. Clark, R.M. 2
  1. 1 Bioinformatics Institute Ghent, Ghent, Belgium
  2. 2 University of Utah
    info

    University of Utah

    Salt Lake City, Estados Unidos

    ROR https://ror.org/03r0ha626

  3. 3 University of Western Ontario
    info

    University of Western Ontario

    London, Canadá

    ROR https://ror.org/02grkyz14

  4. 4 Ghent University
    info

    Ghent University

    Gante, Bélgica

    ROR https://ror.org/00cv9y106

  5. 5 University of Pretoria
    info

    University of Pretoria

    Pretoria, Sudáfrica

    ROR https://ror.org/00g0p6g84

  6. 6 Flanders Institute for Biotechnology
    info

    Flanders Institute for Biotechnology

    Gante, Bélgica

    ROR https://ror.org/03xrhmk39

  7. 7 University of Amsterdam
    info

    University of Amsterdam

    Ámsterdam, Holanda

    ROR https://ror.org/04dkp9463

  8. 8 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

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Revista:
Genome Biology and Evolution

ISSN: 1759-6653

Año de publicación: 2016

Volumen: 8

Número: 11

Páginas: 3323-3339

Tipo: Artículo

DOI: 10.1093/GBE/EVW249 PMID: 27797949 SCOPUS: 2-s2.0-85028398107 WoS: WOS:000393815300007 GOOGLE SCHOLAR

Otras publicaciones en: Genome Biology and Evolution

Resumen

While mechanisms to detoxify plant produced, anti-herbivore compounds have been associated with plant host use by herbivores, less is known about the role of chemosensory perception in their life histories. This is especially true for generalists, including chelicerate herbivores that evolved herbivory independently from the more studied insect lineages. To shed light on chemosensory perception in a generalist herbivore, we characterized the chemosensory receptors (CRs) of the chelicerate two-spotted spider mite, Tetranychus urticae, an extreme generalist. Strikingly, T. urticae has more CRs than reported in any other arthropod to date. Including pseudogenes, 689 gustatory receptors were identified, as were 136 degenerin/Epithelial Na+ Channels (ENaCs) that have also been implicated as CRs in insects. The genomic distribution of T. urticae gustatory receptors indicates recurring bursts of lineage-specific proliferations, with the extent of receptor clusters reminiscent of those observed in the CR-rich genomes of vertebrates or C. elegans Although pseudogenization of many gustatory receptors within clusters suggests relaxed selection, a subset of receptors is expressed. Consistent with functions as CRs, the genomic distribution and expression of ENaCs in lineage-specific T. urticae expansions mirrors that observed for gustatory receptors. The expansion of ENaCs in T. urticae to > 3-fold that reported in other animals was unexpected, raising the possibility that ENaCs in T. urticae have been co-opted to fulfill a major role performed by unrelated CRs in other animals. More broadly, our findings suggest an elaborate role for chemosensory perception in generalist herbivores that are of key ecological and agricultural importance. © The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.