Synthesis of Substituted Benzoquinolines by the Irradiation of 3-Amino-2-alkene Imines

  1. Campos, P.J. 1
  2. Añón, E. 1
  3. Malo, M.C. 1
  4. Tan, C.-Q. 1
  5. Rodríguez, M.A. 1
  1. 1 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

  2. 2 University of Dalian, Dalian, China
Journal:
Tetrahedron

ISSN: 0040-4020

Year of publication: 1998

Volume: 54

Issue: 24

Pages: 6929-6938

Type: Article

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DOI: 10.1016/S0040-4020(98)00374-3 SCOPUS: 2-s2.0-0032507982 WoS: WOS:000073825300027 GOOGLE SCHOLAR

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Abstract

The irradiation of 3-(naphthylamino)-2-alkene imines allows the preparation of substituted benzoquinolines with good to high yields. The reaction can be extended to include polycyclic azacompounds that contain four rings and is suitable for the preparation of halogenated benzoquinolines that can be functionalized further to give derivatives with pharmacological activity.