Development and Validation of Chromatographic Methods (L.C. and G.C.) for the Determination of the Active Components (Benzocaine, Tyrothricin and Menthol) of a Pharmaceutical Preparation
- Ortiz-Boyer, F. 1
- Tena, M.T. 1
- Luque de Castro, M.D. 1
- Valcárcel, M. 1
-
1
Universidad de Córdoba (Colombia)
info
ISSN: 0731-7085
Année de publication: 1995
Volumen: 13
Número: 11
Pages: 1297-1303
Type: Article
beta Ver similares en nube de resultadosD'autres publications dans: Journal of Pharmaceutical and Biomedical Analysis
Résumé
Methods are reported for the determination of tyrothricin and benzocaine by in the analysis of throat lozenges (tablets) containing all three compounds. After optimization of the variables involved in both HPLC and GC the methods hate been characterized and validated according to the guidelines of the Spanish Pharmacopoeia, and applied to both the monitoring of the manufacturing. process and the quality control of the final product.