Flow-Through Photometric Sensor for Determination of Sulphonamides

  1. Tena, M.T. 1
  2. Luque de Castro, M.D. 1
  3. Valcarcel, M. 1
  1. 1 Universidad de Córdoba
    info

    Universidad de Córdoba

    Córdoba, España

    ROR https://ror.org/05yc77b46

Revista:
The Analyst (London. 1877. Print)

ISSN: 0003-2654

Año de publicación: 1994

Volumen: 119

Número: 7

Páginas: 1625-1628

Tipo: Artículo

DOI: 10.1039/AN9941901625 PMID: 7943751 SCOPUS: 2-s2.0-0028122316 GOOGLE SCHOLAR

Otras publicaciones en: The Analyst (London. 1877. Print)

Resumen

A sensor based on integration of spectrophotometric detection and retention of the product of the Bratton-Marshall reaction for the determination of sulfanilamide, sulfamethazine, sulfaquinoxaline and sulfathiazole is reported. The methods developed using this sensor in a flow injection manifold feature linear ranges for these analytes between 10 and 1200 ng ml -1 with relative standard deviations smaller than 2.6% in all instances and they were applied to the determination of sulfonamides in spiked milk and water samples with excellent results. The two main advantages of these sensor-based methods over other automated and non-automated counterparts are enhanced sensitivity as a result of in situ concentration and avoidance of using a de-bubbler to eliminate the nitrogen produced in the flowing system.