Flow-Through Photometric Sensor for Determination of Sulphonamides
- Tena, M.T. 1
- Luque de Castro, M.D. 1
- Valcarcel, M. 1
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1
Universidad de Córdoba
info
ISSN: 0003-2654
Año de publicación: 1994
Volumen: 119
Número: 7
Páginas: 1625-1628
Tipo: Artículo
Otras publicaciones en: The Analyst (London. 1877. Print)
Resumen
A sensor based on integration of spectrophotometric detection and retention of the product of the Bratton-Marshall reaction for the determination of sulfanilamide, sulfamethazine, sulfaquinoxaline and sulfathiazole is reported. The methods developed using this sensor in a flow injection manifold feature linear ranges for these analytes between 10 and 1200 ng ml -1 with relative standard deviations smaller than 2.6% in all instances and they were applied to the determination of sulfonamides in spiked milk and water samples with excellent results. The two main advantages of these sensor-based methods over other automated and non-automated counterparts are enhanced sensitivity as a result of in situ concentration and avoidance of using a de-bubbler to eliminate the nitrogen produced in the flowing system.